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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
65 Results for "
Calcineurin
" in MedChemExpress (MCE) Product Catalog:
Products (65)
65 Results for "Calcineurin" in MCE Product Catalog:
223
223 Publications Verification
Cat. No.: HY-B0579
CAS No.: 59865-13-3
Synonyms: Cyclosporine A; Ciclosporin A; CsA
111
111 Cited Publications
Synonyms: FK506; Fujimycin; FR900506
111
111 Cited Publications
Synonyms: FK506 monohydrate; Fujimycin monohydrate; FR900506 monohydrate
18
Research Areas:
7
7 Cited Publications
Cat. No.: HY-19749
CAS No.: 181765-30-0
Target:
Research Areas:
PD 151746 is a selective calpain-1 inhibitor with an IC50 of 260 nM. PD 151746 binds μ-calpain Ca 2+-binding sites, and shows selectivity over cathepsin B, papain, trypsin, thermolysin, and basal calcineurin. PD 151746 reduces Oxidized low-density lipoprotein (oxLDL)-induced cytotoxicity, apoptotic DNA fragmentation, and blocks IL-1α maturation. PD 151746 can be used for the research of atherosclerosis and psoriasis .
6
Target:
Research Areas:
Pimecrolimus (SDZ-ASM 981) is a potent, nonsteroid and orally active calcineurin inhibitor with a Ki of 117 nM. Pimecrolimus shows anti-inflammatory activity .
5
5 Cited Publications
Synonyms: Triptycene-1,4-quinone
Research Areas:
INCA-6 (Triptycene-1,4-quinone) is a cell-permeable NFAT inhibitor. INCA-6 specifically blocks targeting of NFAT(P) substrate to the calcineurin (CN) phosphatase site and is an effective inhibitor of CN-NFAT signaling .
4
4 Cited Publications
Cat. No.: HY-N0617
CAS No.: 80651-76-9
Category:
Cardiovascular Disease Moraceae Extract Morus alba Linn. Extract Flavanonols Plant Flavonoids Phenols Polyphenols Disease Research Fields Inflammation/Immunology
Target:
1
Target:
Research Areas:
Voclosporin (ISAtx-247) is a calcineurin (PP2B) (CN) inhibitor .
1
1 Cited Publications
Synonyms: FK506-13C,d2; Fujimycin-13C,d2; FR900506-13C,d2
1
1
1
1 Cited Publications
Cat. No.: HY-P1247
CAS No.: 148067-21-4
Target:
Research Areas:
1
1 Cited Publications
Cat. No.: HY-P76759
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PPP3CA; Protein Phosphatase 2B, Catalytic Subunit, Alpha Isoform; Prev. CALNA; Protein Phosphatase 3, Catalytic Subunit, Alpha Isozyme; Prev. CALN; Protein Phosphatase 3 Catalytic Subunit Alpha Isozyme; Calcineurin A Alpha; Serine/Threonine-Protein Phosph
Species:
Human
Source:
Sf9 insect cells
Research Areas:
Glutathione reductase, baker's yeast (EC 1.6.4.2) is a reductase. Glutathione reductase, baker's yeast eliminates intracellular ROS. Glutathione reductase, baker's yeast reduces oxidized glutathione (GSSG) to reduced glutathione (GSH) using NADPH as an electron donor. Glutathione reductase, baker's yeast exerts antioxidant activity. Glutathione reductase is mainly used to study diseases associated with oxidative stress, such as Parkinson's disease and sickle cell anemia .
Cat. No.: HY-W019721
CAS No.: 63775-96-2
Cat. No.: HY-B2006
CAS No.: 51630-58-1
Research Areas:
Fenvalerate is a potent protein phosphatase 2B (calcineurin) inhibitor with an IC50 of 2-4 nM for PP2B-Aα. Fenvalerate is a pyrethroid ester insecticide and acaricide .
Cat. No.: HY-B0579R
CAS No.: 59865-13-3
Synonyms: Cyclosporine A (Standard); Ciclosporin A (Standard); CsA (Standard)
Category:
Cat. No.: HY-13756R
CAS No.: 104987-11-3
Synonyms: FK506 (Standard); Fujimycin (Standard); FR900506 (Standard)
Target:
-
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
