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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
478 Results for "
Cannabinoid Receptor
" in MedChemExpress (MCE) Product Catalog:
Products (478)
478 Results for "Cannabinoid Receptor" in MCE Product Catalog:
27
27 Publications Verification
Target:
Research Areas:
AM251 is a selective cannabinoid 1 (CB1) receptor antagonist with an IC50 of 8 nM. AM251 also acts as a potent GPR55 agonist with an EC50 of 39 nM .
16
16 Cited Publications
Synonyms: SR 141716A Hydrochloride
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Research Areas:
Rimonabant Hydrochloride (SR 141716A Hydrochloride) is a highly potent and selective central cannabinoid receptor (CB1) antagonist with an Ki of 1.8 nM. Rimonabant Hydrochloride (SR 141716A Hydrochloride) also inhibits Mycobacterial membrane protein Large 3 (MMPL3).
16
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Rimonabant (SR141716) is a highly potent, brain penetrated and selective central cannabinoid receptor (CB1) antagonist with a Ki of 1.8 nM. Rimonabant (SR141716) also inhibits Mycobacterial membrane protein Large 3 (MMPL3).
12
12 Cited Publications
Synonyms: 6PPD-Quinone
Category:
Alkaloids Quinones Other Alkaloids Other Diseases Benzene Quinones Endogenous metabolite Disease Research Fields
Target:
10
10 Cited Publications
Cat. No.: HY-18697
CAS No.: 1392116-14-1
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Research Areas:
JD-5037 is a potent CB1R antagonist with an IC50 of 1.5 nM.
8
8 Cited Publications
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Research Areas:
SR144528 is a potent and selective CB2 receptor antagonist with a Ki of 0.6 nM.
7
7
7 Cited Publications
Synonyms: 3β-Hydroxy-5-pregnen-20-one monosulfate sodium
Category:
7
7 Cited Publications
Synonyms: 3β-Hydroxy-5-pregnen-20-one monosulfate
Category:
6
6 Cited Publications
Synonyms: (-)-(E)-Caryophyllene; (−)-β-caryophyllene; (−)-trans-Caryophyllene
3
Target:
Research Areas:
Otenabant is a potent and selective cannabinoid receptor CB1 antagonist with Ki of 0.7 nM, exhibits 10,000-fold greater selectivity against human CB2 receptor.
3
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Research Areas:
Otenabant Hydrochloride is a potent and selective cannabinoid receptor CB1 antagonist with Ki of 0.7 nM, exhibits 10,000-fold greater selectivity against human CB2 receptor.
3
3 Cited Publications
Synonyms: AEA; Arachidonoyl ethanolamide
3
3 Cited Publications
Cat. No.: HY-W011051
CAS No.: 53847-30-6
Category:
2
2 Cited Publications
Synonyms: BZO-HEXOXIZID
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Research Areas:
MDA 19 is a potent and selective agonist of human cannabinoid receptor 2 (CB2), with a Ki of 43.3 nM. MDA 19 has antiallodynic effects in a rat model of neuropathic pain and does not affect rat locomotor activity .
2
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Taranabant is a highly potent and selective cannabinoid 1 (CB1) receptor inverse agonist that inhibits the binding and functional activity of various agonists, with a binding Ki of 0.13 nM for the human CB1R in vitro.
2
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Research Areas:
Olorinab (APD 371) is a highly potent, selective and fully efficacious cannabinoid receptor type 2 (CB2) agonist, with an EC50 of 6.2 nM for hCB2.
2
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Research Areas:
Arachidonylcyclopropylamide (ACPA) is a potent and selective CB1 receptors agonist. Arachidonylcyclopropylamide inhibits forskolin-stimulated cAMP production in CHO cells transfected with human cannabinoid CB1 receptors (IC50=2 nM) .
2
2 Cited Publications
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Research Areas:
AM404, an inhibitor of endocannabinoid reuptake, blocks anandamide transport with IC50 values in the low micromolar range . AM404 is able to relax rat isolated hepatic arteries contracted with Phenylephrine, with a pEC50 value of 7.4 (corresponding to an EC50 of 0.04 μM). Neuroprotective Effect .
2
2 Cited Publications
Cat. No.: HY-B1161A
CAS No.: 65733-16-6
Synonyms: (+)-Methoprene; (7S)-Methoprene
Research Areas:
S-Methoprene is an insect juvenile hormone analog and effective insecticide that blocks the transition from pupa to adult. S-Methoprene is also a CB(1) receptor ligand and inhibits the binding of the CB1 receptor antagonist [ 3H]CP-55940 to the CB1 receptor (IC50: 19.31 μM) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
