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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
325 Results for "
Carbamate
" in MedChemExpress (MCE) Product Catalog:
Products (325)
325 Results for "Carbamate" in MCE Product Catalog:
8
8 Publications Verification
Synonyms: SKF 29044
Target:
Parbendazole (SKF‑29044) is an orally active benzimidazole carbamate compound with multiple biological activities. Parbendazole binds to free tubulin and inhibits microtubule polymerization; it also activates the JNK/c‑Jun signaling axis and upregulates the expression of the downstream axonal repulsion factor Sema3A. Parbendazole upregulates KAL-1 mRNA expression, reduces nerve growth factor levels, and promotes the terminal differentiation of normal human epidermal keratinocytes. Parbendazole induces apoptosis in differentiated acute myeloid leukemia monocytes and exerts antileukemic activity in a mouse xenograft model of acute myeloid leukemia. Parbendazole exhibits broad-spectrum anthelmintic activity against various animal nematodes. Parbendazole is used in research related to acute myeloid leukemia and parasitic infections .
6
6 Cited Publications
Synonyms: 6-Aminoquinolyl-N-hydroxysccinimidyl Carbamate
4
4 Cited Publications
Synonyms: Ethyl Carbamate; Carbamic acid ethyl ester; Ethylurethane
3
3 Cited Publications
Cat. No.: HY-17573
CAS No.: 37025-55-1
Target:
Research Areas:
Carbetocin, an oxytocin (OT) analogue, is an oxytocin receptor agonist with a Ki of 7.1 nM. Carbetocin has high affinity to chimeric N-terminus (E1) of the oxytocin receptor (Ki=1.17 μM). Carbetocin has the potential for postpartum hemorrhage research. Carbetocin can crosse the blood-brain barrier and produces antidepressant-like activity via activation of oxytocin receptors in the CNS .
3
3 Cited Publications
Cat. No.: HY-17573A
CAS No.: 1631754-28-3
Target:
Research Areas:
Carbetocin acetate, an oxytocin (OT) analogue, is an oxytocin receptor agonist with a Ki of 7.1 nM. Carbetocin acetate has high affinity to chimeric N-terminus (E1) of the oxytocin receptor (Ki=1.17 μM). Carbetocin acetate has the potential for postpartum hemorrhage research. Carbetocin acetate can crosse the blood-brain barrier and produces antidepressant-like activity via activation of oxytocin receptors in the CNS .
2
2 Cited Publications
ABC99 is an N-hydroxyhydantoin (NHH) carbamate that selectively inhibits the Wnt-deacylating enzyme NOTUM (IC50=13 nM). ABC99 preserves Wnt3A signaling in the presence of NOTUM .
2
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Research Areas:
Esterase, pig liver (CESs), namely carboxylate hydrolases, are widely distributed in nature, commonly found in mammalian liver, and often used in biochemical research. Esterase catalyzes the hydrolysis of a variety of endogenous and exogenous substrates, including esters, thioesters, carbamates, and amides, hydrolyzing carboxylic acid esters to the corresponding alcohols and carboxylic acids .
1
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Tryptamine guanosine carbamate (TpGc) is a selective HINT1 (histidine triad nucleotide-binding protein 1) inhibitor (Ki=34 μM, Kd=3.65 μM). Tryptamine guanosine carbamate significantly enhances morphine antinociception while preventing the development of tolerance .
1
1 Cited Publications
Cat. No.: HY-N9349
CAS No.: 28500-04-1
1
1 Cited Publications
Cat. No.: HY-W014240
CAS No.: 101-21-3
Target:
Research Areas:
Chlorpropham is a carbamate herbicide and plant growth regulator. Chlorpropham inhibits mitosis and cell division by interfering with the organisation of the spindle microtubules .
1
1 Cited Publications
Cat. No.: HY-W015635
CAS No.: 2179-57-9
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Research Areas:
Chlorphenesin carbamate is a centrally acting skeletal muscle relaxant, as well as a derivate of Chlorphenesin (HY-A0133). Chlorphenesin carbamate can be used for the research of pain and discomfort related to skeletal muscle trauma and inflammation . Chlorphenesin carbamate is a selective blocker of polysynaptic pathways at the spinal and supra-spinal levels . Antinociceptive effect .
Cat. No.: HY-40172
CAS No.: 75178-96-0
Synonyms: NCD
Target:
Research Areas:
Naphthyridine carbamate dimer (NCD) is a molecular glue. Naphthyridine carbamate dimer induces designed structural changes in target functional DNA, thereby regulating its function. As a molecular glue, naphthyridine carbamate dimer stabilizes non-spontaneously formed GG homologous mismatched double-stranded DNA. Naphthyridine carbamate dimer reduces the formation of toxic RNA foci and regulates CGG repeat instability associated with fragile X syndrome and spinocerebellar ataxia type 31. Naphthyridine carbamate dimer can be used in research related to fragile X syndrome and spinocerebellar ataxia type 31 .
Cat. No.: HY-77483
CAS No.: 83948-54-3
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tert-butyl (5-bromopentyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
Cat. No.: HY-Y1401S
CAS No.: 124522-32-3
Cat. No.: HY-W008518
CAS No.: 18807-71-1
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Benzyl N-(2-aminoethyl)carbamate hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs.
Cat. No.: HY-40177
CAS No.: 442514-22-9
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Research Areas:
tert-Butyl (3-(methylamino)propyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
Cat. No.: HY-Z0809
CAS No.: 95656-86-3
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tert-Butyl (2-hydroxypropyl)carbamate is a drug impurity.
Cat. No.: HY-W101721
CAS No.: 95388-79-7
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Research Areas:
tert-Butyl (4-chlorobutyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
