57 Results for "

Chitinase

" in MedChemExpress (MCE) Product Catalog:
Products (57)

57 Results for "Chitinase" in MCE Product Catalog:

Chitinase
Chitinase
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Cat. No.: HY-P2797B
CAS No.: 9001-06-3
Target:  

Biochemical Assay Reagents

Research Areas:  

Inflammation/Immunology

Chitinase is a chitin-targeting enzyme with chitin hydrolysis activity. Chitinase inhibits chitin-induced innate type 2 inflammation in the lung. Chitinase augments chitin-free, allergen-induced Th2 inflammation. Chitinase mediates effector functions of IL-13 .
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Closantel
Closantel
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13 Publications Verification
Cat. No.: HY-17596
CAS No.: 57808-65-8
Target:  

Parasite

Research Areas:  

Infection

Closantel is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel inhibits the O. volvulus L3 to L4 molt of developing .
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Closantel sodium
Closantel sodium
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13 Publications Verification
Cat. No.: HY-17596A
CAS No.: 61438-64-0
Target:  

Parasite

Research Areas:  

Infection

Closantel sodium is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel sodium is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel sodium inhibits the O. volvulus L3 to L4 molt of developing .
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CHI3L1 Protein, Human (HEK293, His)
CHI3L1 Protein, Human (HEK293, His)
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5 Cited Publications
Cat. No.: HY-P70030
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CHI3L1; HCGP-39; Chitinase 3 Like 1; CGP-39; Chitinase-3-Like Protein 1; YKL-40; YKL40; GP-39; YK-40; CHI3L1 Protein; GP39; HC-Gp39; Chitinase 3-Like 1 (Cartilage Glycoprotein-39); HCGP-3P; Cartilage Glycoprotein-39; YYL-40; Cartilage Glycoprotein 39; ASR
Species:  
Human
Source:  
HEK293
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4
Chitinase-like protein 3/YM1 Protein, Mouse (HEK293, His)
Chitinase-like protein 3/YM1 Protein, Mouse (HEK293, His)
0 Images
4 Cited Publications
Cat. No.: HY-P7845
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Ym1; Chi3l3; Chil3; Secreted protein Ym1; Eosinophil chemotactic cytokine; ECF-L; Chitinase-3-like protein 3; Beta-N-acetylhexosaminidase Ym1; EC:3.2.1.52; Chitinase-like protein 3; rMuChitinase-like protein 3/YM1, His
Species:  
Mouse
Source:  
HEK293
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BMS-265246
BMS-265246
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2 Cited Publications
Cat. No.: HY-15275
CAS No.: 582315-72-8
Purity:  99.59%
Target:  

CDK Angiotensin-converting Enzyme (ACE)

Research Areas:  

Infection Cardiovascular Disease Cancer

BMS-265246 is a potent and selective cyclin-dependent kinase CDK1 and CDK2 inhibitor, with IC50 values of 6 and 9 nM, respectively. BMS-265246 inhibits CHI3L1 (chitinase 3-like-1) stimulation of ACE2 (angiotensin converting enzyme 2) and SPP (viral spike protein priming proteases). BMS-265246 can be used for ovarian cancer and COVID-19 research .
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CHI3L1-IN-1
CHI3L1-IN-1
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1 Cited Publications
Cat. No.: HY-163387
CAS No.: 2982256-78-8
Target:  

Glycosidase Potassium Channel

Research Areas:  

Inflammation/Immunology Cancer

CHI3L1-IN-1 (Compound 30) is an inhibitor for Chitinase-3-like protein 1 (CHI3L1) (YKL-40) with IC50 of 50 nM. CHI3L1-IN-1 inhibits hERG channel with an IC50 of 2.3 μM .
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OATD-01
OATD-01
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1 Cited Publications
Cat. No.: HY-137464A
CAS No.: 2088453-21-6
Purity:  99.11%
Target:  

Glycosidase

Research Areas:  

Inflammation/Immunology

OATD-01 is a highly potent, first-in-class, orally active and selective chitinase inhibitor with low nanomolar activity toward CHIT1 (hCHIT1,IC50=23 nM). OATD-01 shows excellect PK profile in multiple species and is selectivity against a panel of other off-targets. OATD-01 exhibits significant antifibrotic efficacy in vivo and can be used for pulmonary fibrosis (IPF) research .
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Chitinase-IN-2 hydrochloride
Chitinase-IN-2 hydrochloride
0 Images
1 Cited Publications
Cat. No.: HY-18599A
CAS No.: 2070014-83-2
Target:  

Insecticide

Research Areas:  

Others

Chitinase-IN-2 hydrochloride is an inhibitor of insect chitinase and N-acetylhexosaminidase.
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Chitinase-IN-2
Chitinase-IN-2
0 Images
1 Cited Publications
Cat. No.: HY-18599
CAS No.: 1579991-63-1
Target:  

Insecticide

Research Areas:  

Others

Chitinase-IN-2 is an insecticide that can inhibit the activity of chitinase and N-acetylhexosaminidase, with inhibition percentages of 98% and 92% at concentrations of 50 μM and 20 μM, respectively.
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CHI3L1 Protein, Mouse (HEK293, His)
CHI3L1 Protein, Mouse (HEK293, His)
0 Images
1 Cited Publications
Cat. No.: HY-P76702
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CHI3L1; HCGP-39; Chitinase 3 Like 1; CGP-39; Chitinase-3-Like Protein 1; YKL-40; YKL40; GP-39; YK-40; CHI3L1 Protein; GP39; HC-Gp39; Chitinase 3-Like 1 (Cartilage Glycoprotein-39); HCGP-3P; Cartilage Glycoprotein-39; YYL-40; Cartilage Glycoprotein 39; ASR
Species:  
Mouse
Source:  
HEK293
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Chitin, from shrimp shells (chitinase substrate)
Chitin, from shrimp shells (chitinase substrate)
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Cat. No.: HY-126389B
CAS No.: 1398-61-4
Chitin, from shrimp shells (chitinase substrate) serves as a substrate for chitinase. Chitin, from shrimp shells (chitinase substrate) is a long-chain polymer of N-acetylglucosamine with β-(1-4) linkages. Chitin, from shrimp shells (chitinase substrate) is found in the exoskeleton of crabs. Chitin, from shrimp shells (chitinase substrate) inhibits the activation of NF-κB p65, alters the translocation of NF-κB p65 to the nucleus, and interacts with the cell wall of Candida species. Chitin, from shrimp shells (chitinase substrate) exerts antifungal and anti-inflammatory effects. Chitin, from shrimp shells (chitinase substrate) can be used in the research of gastric ulcer and candidiasis .
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Chitinase, Streptomyces griseus
Chitinase, Streptomyces griseus
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Cat. No.: HY-P2797A
CAS No.: 9001-06-3
Synonyms: AMCase, Streptomyces griseus
Target:  

Biochemical Assay Reagents

Research Areas:  

Others

Chitinase, Streptomyces griseus is a chitinase from Streptomyces griseus. Chitinase is a chitin-targeting enzyme with chitin hydrolysis activity. Chitinase inhibits chitin-induced innate type 2 inflammation in the lung. Chitinase augments chitin-free, allergen-induced Th2 inflammation. Chitinase mediates effector functions of IL-13 .
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Cyclo(Arg-Pro)
Cyclo(Arg-Pro)
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Cat. No.: HY-P10304
CAS No.: 74838-83-8
Synonyms: Cyclo(Pro-Arg)
Target:  

Fungal

Research Areas:  

Others

Cyclo(Arg-Pro) (Cyclo(Pro-Arg)) is an inhibitor for chitinase. Cyclo(Arg-Pro) inhibits cell separation of Saccharomyces cerevisiae, without affecting its growth. Cyclo(Arg-Pro) inhibits the morphological change of Candida albicans from yeast form to filamentous form .
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Chitinase, Serratia marcescens
Chitinase, Serratia marcescens
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Cat. No.: HY-P2797
CAS No.: 9001-06-3
Synonyms: AMCase, Serratia marcescens
Target:  

Biochemical Assay Reagents

Research Areas:  

Metabolic Disease Inflammation/Immunology

Chitinase, Serratia marcescens is a chitinase from Serratia marcescens. Chitinase is a chitin-targeting enzyme with chitin hydrolysis activity. Chitinase inhibits chitin-induced innate type 2 inflammation in the lung. Chitinase augments chitin-free, allergen-induced Th2 inflammation. Chitinase mediates effector functions of IL-13 .
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Argifin
Argifin
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Cat. No.: HY-P2274
CAS No.: 243975-37-3
Category:  

Infection Natural Products Microorganisms Disease Research Fields

Target:  

Parasite

Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC50s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively .
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Sennidin B
Sennidin B
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Cat. No.: HY-N6935
CAS No.: 517-44-2
Category:  

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