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10 Results for "

Communic acid

" in MedChemExpress (MCE) Product Catalog:

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Communic acid

Cat. No.: HY-N3612

CAS No.: 2761-77-5

Synonyms: (+)-Communic acid

Category:

Animals Ketones, Aldehydes, Acids

Target:

Bacterial Akt MMP

Communic acid ((+)-Communic acid) is a natural compound isolated from the branches of Platycladus orientalis. Communic acid displays minimum inhibitory concentration of 31 μM and IC₅₀ of 15 μM against M. tuberculosis H37Ra.Communic acid exhibits protective effects against UVB-induced skin aging .

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Schizophyllan

Cat. No.: HY-165126

CAS No.: 9050-67-3

Synonyms: SPG

Target:

C-type Lectin-like Receptors (CTLRs) Endogenous Metabolite Sirtuin JNK p38 MAPK PPAR AP-1

Research Areas:

Infection Metabolic Disease Inflammation/Immunology Cancer

Schizophyllan (SPG) is an orally active extracellular β-glucan produced by the fungus Schizophyllum commune. Schizophyllan improves mitochondrial function and protects against metabolic liver injury by activating the SIRT3 pathway. Schizophyllan inhibits osteoclastogenesis and promotes osteoblast differentiation by suppressing the phosphorylation of JNK/p38, as well as downregulating PGC1β/PPARγ, c-Fos and NFATc1. Recognized via Dectin-1, schizophyllan enables precise delivery of oligonucleotide drugs and antigens to antigen-presenting cells, thus holding great potential in the treatment of inflammatory diseases and vaccine development .

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