36 Results for "

Complement C3 Antibody

" in MedChemExpress (MCE) Product Catalog:
Products (36)

36 Results for "Complement C3 Antibody" in MCE Product Catalog:

Cat. No.: HY-P99050
CAS No.: 2049079-64-1
Synonyms: BIVV009; IPN-009; TNT009

Target:  

Complement System

Research Areas:  

Endocrinology

Sutimlimab is a humanized monoclonal IgG4 antibody. Sutimlimab inhibits complement protein component 1, s subcomponent (C1s). Sutimlimab blocks C3 and C4 activation. Sutimlimab can be used for the research of cold agglutinin disease and complement-mediated hemolytic uremic syndrome .
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Cat. No.: HY-P990091
CAS No.: 2756228-76-7
Synonyms: SAR445088
Riliprubart (SAR445088) is a selective anti-C1s humanized IgG4 monoclonal antibody with mutations that enhance its binding to the neonatal Fc receptor. Riliprubart blocks activation of the classical complement pathway, prevents the formation of the C3 convertase C4b2a, and inhibits complement-mediated hemolytic activity. Riliprubart can be used in research related to classical complement-mediated diseases, cold agglutinin disease, and chronic inflammatory demyelinating polyneuropathy. For the isotype control of Riliprubart, refer to Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
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Cat. No.: HY-P990025
CAS No.: 2579031-19-7
Synonyms: ARGX-117

Target:  

Complement System

Research Areas:  

Inflammation/Immunology

Empasiprubar (ARGX-117) is a humanized inhibitory monoclonal antibody targeting complement C2. Empasiprubar binds to the Sushi-2 domain of C2, preventing the formation of C3 pre convertase and inhibiting the activation of classical and lectin pathways upstream of C3 activation. Empasiprubar can prevent complement mediated autoimmune hemolytic anemia and antibody mediated organ transplant rejection. Empasiprubar can prevent neuroglial lymphoconjunctival injury in GM1 antibody mediated mouse models .
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Cat. No.: HY-P990637

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

NGM-621 is a CHO-expressed human antibody that targets Complement C3. NGM-621 contains a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 149.04 kDa. The isotype control for NGM-621 can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P990955
CAS No.: 2839652-75-2
Synonyms: ADX-097

Target:  

CD3 Complement System

Research Areas:  

Inflammation/Immunology

Ebribafusp alfa (ADX-097) comprising a humanized anti-C3d monoclonal antibody linked to two moieties of the first five consensus repeats of factor H (fH1-5). Ebribafusp alfa binds C3d and related fragments, catalyzes AP convertase dissociation, acts as a factor I co-factor for C3b cleavage, and delivers fH1-5 moieties to C3d-deposited tissues for local complement inhibition without systemic blockade. Ebribafusp alfa reduces glomerular C3 deposition, proteinuria, urine albumin-creatinine ratios, and urine soluble C5b-9 levels, preserves podocyte foot-process architecture, inhibits skin complement activation, and localizes to UVB-damaged primate skin. Ebribafusp alfa can be used for the research of membranous nephropathy, bullous pemphigoid, discoid lupus erythematosus, C3 glomerulopathy, IgA nephropathy, and lupus nephritis .
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Cat. No.: HY-P80577
Synonyms: CPAMD1; C3; Complement C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human

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Cat. No.: HY-P87675
Synonyms: CPAMD1; C3; Complement C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P80577A
Synonyms: CPAMD1; C3; Complement C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human

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Cat. No.: HY-P83897
Synonyms: CPAMD1; C3; Complement C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1

Host:  

Mouse

Application:  

WB, IHC-P, ICC/IF, FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P812069
Synonyms: CPAMD1; C3; Complement C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1

Host:  

Rabbit

Application:  

WB, ICC/IF, FC

Reactivity:  

Human

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Cat. No.: HY-P83897A
Synonyms: CPAMD1; C3; Complement C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1

Host:  

Mouse

Application:  

WB, IHC-P, ICC/IF, FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P992456
Target:  

Complement System

SAR-443809 is a monoclonal antibody targeting complement factor Bb that inhibits the alternative complement pathway. SAR-443809 blocks the cleavage of C3 and factor B via selective binding to the activated form factor Bb, with a KD of 7.3 nM for human factor Bb. SAR-443809 inhibits the amplification loop of the alternative complement pathway and C3 activation, reduces C3b deposition, and blocks the activation of pathways associated with intravascular and extravascular hemolysis. SAR-443809 can be used for research on hematological and renal disorders mediated by abnormal alternative complement pathway activity .
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Cat. No.: HY-P83954
Synonyms: CD18; Integrin beta-2; Complement receptor C3 subunit beta; Itgb2

Host:  

Mouse

Application:  

WB, FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P85085
Synonyms: CD18; Integrin beta-2; Complement receptor C3 subunit beta; Itgb2

Host:  

Mouse

Application:  

ICC/IF, ELISA

Reactivity:  

Human, Mouse

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Cat. No.: HY-P83046
Synonyms: DF; PFD; CFD; Complement factor D; Adipsin; C3 convertase activator; Properdin factor D

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human

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Cat. No.: HY-P83046A
Synonyms: DF; PFD; CFD; Complement factor D; Adipsin; C3 convertase activator; Properdin factor D

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human

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Cat. No.: HY-P83954A
Synonyms: CD18; Integrin beta-2; Complement receptor C3 subunit beta; Itgb2

Host:  

Mouse

Application:  

WB, FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P80795
Synonyms: CD18; Integrin beta-2; Complement receptor C3 subunit beta; Itgb2

Host:  

Rabbit

Application:  

WB, IP

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P86840
Synonyms: CPAMD4; C5; Complement C5; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4

Host:  

Rabbit

Application:  

WB, ICC/IF, IHC-P, FC

Reactivity:  

Human

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Cat. No.: HY-P80795A
Synonyms: CD18; Integrin beta-2; Complement receptor C3 subunit beta; Itgb2

Host:  

Rabbit

Application:  

WB, IP

Reactivity:  

Human, Mouse, Rat

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