37 Results for "

Con-S

" in MedChemExpress (MCE) Product Catalog:
Products (37)

37 Results for "Con-S" in MCE Product Catalog:

15
Dasabuvir
Dasabuvir
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15 Publications Verification
Cat. No.: HY-13998
CAS No.: 1132935-63-7
Purity:  98.17%
Synonyms: ABT-333
Target:  

HCV DNA/RNA Synthesis

Research Areas:  

Infection

Dasabuvir (ABT-333) is a nonnucleoside hepatitis C virus (HCV) polymerase inhibitor. Dasabuvir inhibits RNA-dependent RNA polymerase encoded by the HCV NS5B gene. Dasabuvir inhibits genotype 1a (strain H77) and 1b (strain Con1) replicons, with EC50 values of 7.7 and 1.8 nM, respectively .
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8
PSI-7409 tetrasodium
PSI-7409 tetrasodium
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8 Cited Publications
Cat. No.: HY-15745A
CAS No.: 1621884-22-7
Purity:  99.31%
Target:  

HCV

Research Areas:  

Infection

PSI-7409 tetrasodium is an active 5'-triphosphate metabolite of sofosbuvir (PSI-7977), inhibiting HCV NS5B polymerases, with IC50s of 1.6, 2.8, 0.7 and 2.6 μM for GT 1b_Con1, GT 2a_JFH1, GT 3a, and GT 4a NS5B polymerases, respectively.
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4
Elironrasib
Elironrasib
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4 Cited Publications
Cat. No.: HY-153346
CAS No.: 2641998-63-0
Purity:  99.65%
Synonyms: RMC-6291
Target:  

Ras ERK Apoptosis

Research Areas:  

Cancer

Elironrasib is an orally active and covalent inhibitor of KRAS G12C(ON). Elironrasib forms a tri-complex within tumor cells between KRAS G12C(ON) and cyclophilin A (CypA). Thus, Elironrasib prevents KRAS G12C(ON) from signaling via steric blockade of RAS effector binding. Elironrasib inhibits ERK signaling and induced apoptosis in KRASG12C-mutant H358 cells. Elironrasib also inhibits the proliferation of KRAS G12C mutant cells with a median IC50 of 0.11 nM .
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2
Lomibuvir
Lomibuvir
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2 Cited Publications
Cat. No.: HY-75800
CAS No.: 1026785-55-6
Synonyms: VX-222
Target:  

DNA/RNA Synthesis HCV

Research Areas:  

Infection

Lomibuvir (VX-222), a selective, non-nucleoside polymerase inhibitor, targets thumb pocket 2 of the HCV NS5B polymerase (RdRp) with a Kd of 17 nM. Lomibuvir inhibits the 1b/Con1 HCV subgenomic replicon with an EC50 of 5.2 nM. Lomibuvir preferentially inhibits elongative RNA synthesis rather than de novo-initiated RNA synthesis .
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1
Concanavalin A (Biotinylated)
Concanavalin A (Biotinylated)
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1 Cited Publications
Cat. No.: HY-NP0174
Synonyms: Con A (Biotinylated)
Concanavalin A (Con A) Biotinylated is a biological material or organic compound that can be used in life science research .
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Concanavalin A-HRP
Concanavalin A-HRP
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Cat. No.: HY-NP164
Synonyms: Con A-HRP
Concanavalin A-HRP (Con A-HRP) is a HRP-labled Concanavalin A (HY-P2149). Concanavalin A is a Ca 2+/Mn 2+-dependent and mannose/glucose-binding plant lectin. Concanavalin A binds the N- and O-glycosylated proteins of head and neck carcinoma cells glycoproteins .
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4,5-Dibromo-2-pyrrolic acid
4,5-Dibromo-2-pyrrolic acid
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Cat. No.: HY-W340234
CAS No.: 34649-21-3
Category:  

Animals Ketones, Aldehydes, Acids

Target:  

Galectin

4,5-Dibromo-2-pyrrolic acid (compound 2) is an immunosuppressive compound. 4,5-Dibromo-2-pyrrolic acid suppresses the proliferative response of splenocytes to suboptimal concentrations of the mitogen, concanavalin A (Con A) .
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Conopressin S
Conopressin S
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Cat. No.: HY-P1737
CAS No.: 111317-90-9
Synonyms: Con-S
Target:  

Inhibitory Antibodies

Research Areas:  

Cardiovascular Disease

Conopressin S, isolated from Conus striatus, shows high affinity with vasopressin V1b receptor (AVPR1B), with a Ki of 8.3 nM .
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Concanavalin A-AF488
Concanavalin A-AF488
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Cat. No.: HY-NP164B
Synonyms: Con A-AF488
Concanavalin A-AF488 (Con A-AF488) is an AF488-labled Concanavalin A (HY-P2149). Concanavalin A is a Ca 2+/Mn 2+-dependent and mannose/glucose-binding plant lectin. Concanavalin A binds the N- and O-glycosylated proteins of head and neck carcinoma cells glycoproteins .
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Concanavalin A (Fluorescein)
Concanavalin A (Fluorescein)
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Cat. No.: HY-NP096
Synonyms: Con A (Fluorescein)
Concanavalin A (Con A) (Con A) Fluorescein is a biological material or organic compound that can be used in life science research .
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11R-CaN-CON
11R-CaN-CON
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Cat. No.: HY-P10168
Target:  

Phosphatase

Research Areas:  

Others

11R-CaN-CON is a control inactive peptide and can be used as a negative control for 11R-CaN-AID (HY-P10167) .
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Dasabuvir sodium
Dasabuvir sodium
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Cat. No.: HY-13998A
CAS No.: 1132940-11-4
Synonyms: ABT-333 sodium
Target:  

HCV DNA/RNA Synthesis

Research Areas:  

Infection

Dasabuvir (ABT-333) sodium is a nonnucleoside hepatitis C virus (HCV) polymerase inhibitor. Dasabuvir sodium inhibits RNA-dependent RNA polymerase encoded by the HCV NS5B gene. Dasabuvir sodium inhibits genotype 1a (strain H77) and 1b (strain Con1) replicons, with EC50 values of 7.7 and 1.8 nM, respectively .
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cis-Lomibuvir
cis-Lomibuvir
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Cat. No.: HY-114571
CAS No.: 1026785-59-0
Synonyms: cis-VX-222
Target:  

DNA/RNA Synthesis HCV

Research Areas:  

Infection

cis-Lomibuvir (cis-VX-222) is the cis-isomer of Lomibuvir. Lomibuvir (VX-222), a selective, non-nucleoside polymerase inhibitor, targets thumb pocket 2 of the HCV NS5B polymerase (RdRp) with a Kd of 17 nM. Lomibuvir inhibits the 1b/Con1 HCV subgenomic replicon with an EC50 of 5.2 nM. Lomibuvir preferentially inhibits elongative RNA synthesis rather than de novo-initiated RNA synthesis . cis-Lomibuvir is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Concanavalin A (Rhodamine)
Concanavalin A (Rhodamine)
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Cat. No.: HY-NP0153
Synonyms: Con A (Rhodamine)
Concanavalin A (Con A) Rhodamine is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Concanavalin A (Con A) Rhodamine is a biological material or organic compound that can be used in life science research .
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Homodestcardin
Homodestcardin
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Cat. No.: HY-P3107
CAS No.: 917382-84-4
Category:  

Microorganisms Cyclopeptides Disease Research Fields Inflammation/Immunology

Target:  

Endogenous Metabolite

Homodestcardin, a destruxinbased cyclodepsipeptide, is a immunosuppressant. Homodestcardin, a fungal metabolite, displays pronounced activities against concanavalin A (Con A) activation, with an IC50 value of 0.86 μM .
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PTC 725
PTC 725
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Cat. No.: HY-12732
CAS No.: 1248581-07-8
Target:  

HCV

Research Areas:  

Infection

PTC 725 is a potent, selective and orally active Hepatitis C Virus NS4B Protein inhibitor. PTC 725 inhibits HCV 1b (Con1) replicons .
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Saucerneol
Saucerneol
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Cat. No.: HY-N10092
CAS No.: 88497-86-3
Synonyms: (-)-Saucerneol
Category:  

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