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58 Results for "

Cortical neuron

" in MedChemExpress (MCE) Product Catalog:

Products (58)

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Neuropeptide Y (human,rat,mouse)

4 Cited Publications

Cat. No.: HY-P0198

CAS No.: 90880-35-6

Synonyms: Neuropeptide Y (29-64), amide

Target:

Neuropeptide Y Receptor

Research Areas:

Neurological Disease Endocrinology

Neuropeptide Y (human,rat,mouse) is involved in Alzheimer's disease (AD) and protects rat cortical neurons against β-Amyloid toxicity.

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Pifithrin-α, p-Nitro, Cyclic

4 Cited Publications

Cat. No.: HY-123076

CAS No.: 60477-38-5

Purity: 99.37%

Synonyms: PFN-α

Target:

MDM-2/p53

Research Areas:

Neurological Disease

Pifithrin-α, p-Nitro, Cyclic (PFN-α) is cell-permeable and active-form p53 inhibitor. Pifithrin-α, p-Nitro, Cyclic is one order magnitude more active than Pifithrin-α in protecting cortical neurons exposed to Etoposide (ED₅₀=30 nM). Pifithrin-α, p-Nitro, Cyclic behaves as a p53 posttranscriptional activity inhibitor. Pifithrin-α, p-Nitro, Cyclic do not prevent p53 phosphorylation on the S15 residue .

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Neuropeptide Y (human,rat,mouse) TFA

4 Cited Publications

Cat. No.: HY-P0198A

Target:

Neuropeptide Y Receptor

Research Areas:

Neurological Disease Endocrinology

Neuropeptide Y (human) TFA is involved in Alzheimer's disease (AD) and protects rat cortical neurons against β-Amyloid toxicity.

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MSN-125

4 Cited Publications

Cat. No.: HY-120079

CAS No.: 1592908-16-1

Purity: 99.00%

Target:

Bcl-2 Family Apoptosis

Research Areas:

Cancer

MSN-125 is a potent Bax and Bak oligomerization inhibitor. MSN-125 prevents mitochondrial outer membrane permeabilization (MOMP) with an IC₅₀ of 4 μM. MSN-125 potently inhibits Bax/Bak-mediated apoptosis in HCT-116, BMK Cells, and primary cortical neurons, protects primary neurons against glutamate excitotoxicity .

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