3

3 Cited Publications

Category:

Target:

Pulcherriminic acid is a cyclic dipeptide antimicrobial agent with high affinity for Fe ³⁺, found mainly in Bacillus and yeast. Pulcherriminic acid chelates iron ions through a non-enzymatic reaction to form the extracellular red pigment pulcherrimin, which competes for iron nutrition and thus achieves an antibacterial effect. Pulcherriminic acid has great applications in food, agriculture and medical industries .

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Cyclo(L-Phe-L-Pro)

1 Cited Publications

Cat. No.: HY-P1934A

CAS No.: 3705-26-8

Category:

Natural Products Microorganisms Disease Research Fields Inflammation/Immunology Cancer

Target:

Free Radical Scavengers Fungal Bacterial IFNAR Reactive Oxygen Species (ROS)

Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide . Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation . Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC₅₀ of 24 µM in the DPPH assay .

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Cyclo(Gly-Tyr)

1 Cited Publications

Cat. No.: HY-131109

CAS No.: 5845-66-9

Purity: 99.70%

Target:

Inhibitory Antibodies

Research Areas:

Others

Cyclo(Gly-Tyr) is a cyclic dipeptide .

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Cyclo(L-Leu-L-Pro)

Cat. No.: HY-P1939

CAS No.: 2873-36-1

Synonyms: Cyclo(L-prolyl-L-leucyl)

Target:

Fungal Bacterial Influenza Virus

Research Areas:

Infection

Cyclo(L-Leu-L-Pro) is a cyclic dipeptide with broad-spectrum antibacterial, antiviral and antifungal activities. Its biological activity is highly dependent on the stereoconfiguration and is widely present in microbial metabolites. Cyclo(L-Leu-L-Pro) efficiently and specifically inhibits the production of aflatoxin by Aspergillus flavus. The cis configuration of Cyclo(L-Leu-L-Pro) (cis-cyclo(L-Leu-L-Pro)) has broad-spectrum antibacterial activity against multi-drug resistant bacteria and significantly inhibits the influenza A virus H3N2 .

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Cyclo(his-pro)

Cat. No.: HY-101402

CAS No.: 53109-32-3

Synonyms: Cyclohistidyl-proline; Histidylproline diketopiperazine

Category:

Natural Products Endogenous metabolite

Target:

NF-κB Endogenous Metabolite

Cyclo(his-pro) (Cyclo(histidyl-proline)) is an orally active cyclic dipeptide structurally related to tyreotropin-releasing hormone . Cyclo(his-pro) could inhibit NF-κB nuclear accumulation. Cyclo(his-pro) can cross the brain-blood-barrier and affect diverse inflammatory and stress responses .

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(R)-5-Oxopyrrolidine-2-carboxylic acid

Cat. No.: HY-W002304

CAS No.: 4042-36-8

Category:

Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields

Target:

Drug Intermediate

(R)-5-Oxopyrrolidine-2-carboxylic acid is a cyclic derivative of D-glutamate, as well as a heterocyclic structural unit and a precursor of cyclic imino acids. (R)-5-Oxopyrrolidine-2-carboxylic acid acts as an intermediate in the synthesis of dipeptide hybrids with antibacterial activity and the synthesis of Δ-1-pyrroline-5-carboxylic acid (P5C). (R)-5-Oxopyrrolidine-2-carboxylic acid is applicable to research related to organic synthesis .

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Leucyl-phenylalanine

Cat. No.: HY-113278

CAS No.: 3063-05-6

Purity: 99.56%

Category:

Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields

Target:

Endogenous Metabolite Drug Intermediate

Leucyl-phenylalanine is a linear dipeptide composed of L-leucine and L-phenylalanine, and also serves as a cyclization substrate. Leucyl-phenylalanine is an incomplete degradation product generated during protein breakdown or catabolism. Leucyl-phenylalanine undergoes heat-induced solid-state cyclization via an autocatalytic mechanism to form its cyclic diketopiperazine analog .

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Cyclo(his-pro) TFA

Cat. No.: HY-101402A

CAS No.: 936749-56-3

Purity: 99.06%

Synonyms: Cyclohistidyl-proline TFA; Histidylproline diketopiperazine TFA

Category:

Natural Products Endogenous metabolite

Target:

NF-κB Endogenous Metabolite

Cyclo(his-pro) TFA (Cyclo(histidyl-proline) TFA) is an orally active cyclic dipeptide structurally related to tyreotropin-releasing hormone . Cyclo(his-pro) TFA could inhibit NF-κB nuclear accumulation. Cyclo(his-pro) TFA can cross the brain-blood-barrier and affect diverse inflammatory and stress responses .

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