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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
Cyclic-di-GMP
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "Cyclic-di-GMP" in MCE Product Catalog:
Cat. No.: HY-107780
CAS No.: 61093-23-0
Synonyms: c-di-GMP; Cyclic diguanylate; 5GP-5GP
Category:
Ketones, Aldehydes, Acids Metabolic Disease Microorganism Endogenous metabolite Disease Research Fields
Target:
10
Category:
Infection Antibiotics Microorganism Disease Research Anticancer Disease Research Fields Other Antibiotics
Target:
9
9 Cited Publications
Synonyms: c-di-GMP disodium; Cyclic diguanylate disodium; 5GP-5GP disodium
Target:
9
9 Cited Publications
Synonyms: c-di-GMP diammonium; Cyclic diguanylate diammonium; 5GP-5GP diammonium
Target:
1
1 Cited Publications
Cat. No.: HY-P1206
CAS No.: 174688-78-9
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Research Areas:
CH 275 is a peptidic somatostatin analog that acts as an agonist of SST1 (IC50 = 30.9 nM, Ki = 52 nM). The IC50 values of CH 275 for sst3, sst4, sst2, and sst5 are 345 nM, >1 μM, >10 μM, and >10 μM, respectively. CH 275 binds to SSTR1 via the IAmp9-Asp137 ion pair interaction and the hydrophobic interaction between the isopropyl group of IAmp9 and Leu107, and reduces the extracellular acidification rate. CH 275 induces weak sst1 internalization, exerts immunosuppressive effects on macrophages, and decreases macrophage viability, MCP-1 expression/secretion, and IL-8 secretion, but does not alter proMMP-9 secretion or IL-8 mRNA levels. CH 275 reduces hippocampal β-amyloid levels and alleviates plaque pathology without inducing hippocampal microglial activation. CH 275 is used in research on Alzheimer's disease, Parkinson's disease, and depression .
Cat. No.: HY-P10033
CAS No.: 245080-24-4
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Research Areas:
Cat. No.: HY-107780A
Synonyms: c-di-GMP sodium; Cyclic diguanylate sodium; 5GP-5GP sodium
Category:
Ketones, Aldehydes, Acids Metabolic Disease Microorganism Endogenous metabolite Disease Research Fields
Target:
Cat. No.: HY-P4102
CAS No.: 1810853-35-0
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Research Areas:
Cat. No.: HY-110382S
Synonyms: c-di-GMP-13C20,15N10 disodium; Cyclic diguanylate-13C20,15N10 disodium; 5GP-5GP-13C20,15N10 disodium
Cat. No.: HY-P3193A
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Cat. No.: HY-P10027A
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Cat. No.: HY-P10027
CAS No.: 2247194-77-8
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Cat. No.: HY-P3193
Target:
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Cat. No.: HY-P10672
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
