120 Results for "

Cyp1a1

" in MedChemExpress (MCE) Product Catalog:
Products (120)

120 Results for "Cyp1a1" in MCE Product Catalog:

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34
2-Methoxyestradiol
2-Methoxyestradiol
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34 Publications Verification
Cat. No.: HY-12033
CAS No.: 362-07-2
Purity:  99.76%
Synonyms: 2-ME2; NSC-659853
Category:  

Monophenols Disease markers Endocrine diseases Phenols Endogenous metabolite Disease Research Fields Cancer Steroids

Target:  

Endogenous Metabolite Microtubule/Tubulin HIF/HIF Prolyl-Hydroxylase Cytochrome P450 JNK Caspase Estrogen Receptor/ERR Reactive Oxygen Species (ROS) Apoptosis Autophagy

2-Methoxyestradiol (2-ME2; NSC-659853) is an endogenous steroid metabolite generated from 17β-estradiol, possessing various activities such as antitumor and antiangiogenic effects. 2-Methoxyestradiol competitively binds to the colchicine-binding site of tubulin (tubulin), interfering with microtubule assembly dynamics. 2-Methoxyestradiol inhibits CYP1A1/CYP1B1, HIF-1α/2α, and superoxide dismutase, activates the JNK signaling pathway, elevates ROS levels, and induces cell cycle arrest and apoptosis (apoptosis). 2-Methoxyestradiol is used in cancer-related research, such as breast cancer, prostate cancer, and multiple myeloma .
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21
Galangin
Galangin
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21 Cited Publications
Cat. No.: HY-N0382
CAS No.: 548-83-4
Synonyms: Norizalpinin; 3,5,7-Trihydroxyflavone
Category:  

Flavonols Zingiberaceae Extract Plants Flavonoids Microorganisms Phenols Polyphenols 500 - Internal Server Error | MedChemExpress

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