4 Results for "

DAF-16

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "DAF-16" in MCE Product Catalog:

Psora-4
Psora-4
0 Images
Cat. No.: HY-108583
CAS No.: 724709-68-6
Purity:  99.7%
Synonyms: 5-(4-Phenylbutoxy)psoralen
Target:  

HSP Reactive Oxygen Species (ROS) Potassium Channel

Research Areas:  

Metabolic Disease Inflammation/Immunology

Psora-4 (5-(4-Phenylbutoxy) psoralen) is a selective Kv1.3 blocker (Kd = 3 nM). Psora-4 increases mitochondrial ROS production, activates stress response genes including daf-16 targets and heat shock proteins, reduces triglyceride accumulation, extends lifespan and healthspan in C. elegans, and increases resistance to Paraquat-induced oxidative stress. Psora-4 can be used for research on psoriasis and obesity .
loading...
    loading...
View All Sizes
M084
M084
0 Images
Cat. No.: HY-133859
CAS No.: 51314-51-3
Target:  

Mitochondrial Metabolism

Research Areas:  

Metabolic Disease

M084 is a benzimidazole derivative. M084 inhibits the mitochondrial respiration, activate mitochondrial unfolded protein response and AMPK, recruites SIR-2.1 and SKN-1, and finally through the transcription factor DAF-16, delays the aging process of C. elegans .
loading...
    loading...
View All Sizes
PSEC13
PSEC13
0 Images
Cat. No.: HY-174438
Target:  

HSP

Research Areas:  

Metabolic Disease

PSEC13 is an activator of HSF-1/DAF-16 axis. PSEC13 can upregulate heat shock proteins. PSEC13 can form hydrogen bonds with key residues in the HSP-16.2 active site. PSEC13 can be used to enhance proteostasis and extend lifespan through the modulation of HSP-16.2. PSEC13 could promote the nuclear translocation of daf-16, upgrading the proportion of intermediate. PSEC13 can be studied in research for aging and age-related diseases .
loading...
    loading...
View All Sizes
Isolappaol A
Isolappaol A
0 Images
Cat. No.: HY-N12526
CAS No.: 131400-96-9
Category:  

Lignans Phenols Polyphenols Phenylpropanoids Plants 500 - Internal Server Error | MedChemExpress

Oops!

Sorry, Something went wrong on our server.
Our team has been notified and is working to fix the issue.