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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
DDX18
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "DDX18" in MCE Product Catalog:
1
Cat. No.: HY-RS03633
Target:
Research Areas:
DDX18 Human Pre-designed siRNA Set A contains three designed siRNAs for DDX18 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-189123
CAS No.: 724429-20-3
Target:
Research Areas:
M12 is a DCAF11-dependent molecular glue degrader activated by glutathionylation, which induces CRL4 DCAF11-mediated degradation of DDX18. M12 is a precursor compound that requires metabolic activation: it is conjugated with glutathione (GSH) under the catalysis of glutathione S-transferase (GST) to form GSH-M12, which interacts with DCAF11 and promotes the recruitment of DDX18. M12 is applicable for studies on targeted protein degradation and DCAF11-dependent molecular glue mechanisms .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
