Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
DDX21
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "DDX21" in MCE Product Catalog:
Cat. No.: HY-175238
CAS No.: 1309288-83-2
Target:
Research Areas:
KI-DX-014 is a DDX21 inhibitor with high RNA-binding inhibitory activity (IC50 of 3.31 μM). KI-DX-014 targets DDX21’s intrinsically disordered C-terminal domain, inhibits DDX21-structured RNA interaction, modulates DDX21’s RNA-dependent ATPase activity, and disrupts DDX21 biomolecular condensate formation. KI-DX-014 attenuates in vitro P-TEFb release from the 7SK snRNP complex, suppresses P-TEFb-dependent RNA polymerase II CTD phosphorylation, and induces developmental defects in zebrafish embryos. KI-DX-014 acts as a chemical probe for dissecting DDX21 functions in normal physiology and disease states. KI-DX-014 can be used for cancers and neurodegenerative disorders research .
Cat. No.: HY-RS03637
Target:
Research Areas:
DDX21 Human Pre-designed siRNA Set A contains three designed siRNAs for DDX21 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS20906
Target:
Research Areas:
Ddx21 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ddx21 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS27423
Target:
Research Areas:
Ddx21 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ddx21 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P705533
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DDX21; DEAD-Box Helicase 21; DExD-Box Helicase 21; DEAD (Asp-Glu-Ala-Asp) Box Helicase 21; Gu-Alpha; RNA Helicase II/Gu Alpha; Nucleolar RNA Helicase 2; DDX21 Protein; Nucleolar RNA Helicase Gu; RNA Helicase; Nucleolar RNA Helicase II; Gu Protein; DEAD Bo
Species:
Human
Source:
E. coli
Cat. No.: HY-P82918A
Synonyms: GUA; GURDB; RH-II/GU; RH-II/GuA
Cat. No.: HY-RS03661
Target:
Research Areas:
DDX56 Human Pre-designed siRNA Set A contains three designed siRNAs for DDX56 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
