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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
DG013A
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "DG013A" in MCE Product Catalog:
Cat. No.: HY-139907
CAS No.: 2007955-07-7
Target:
Research Areas:
DG013A is a zinc-dependent M1-aminopeptidase inhibitor that exhibits inhibitory activity against ERAP1 (IC50 = 33 nM) and ERAP2 (IC50 = 11 nM). DG013A enhances SRHFLAFSFR epitope presentation, rescues GSW11 peptide neoantigen presentation, reduces SIINFEKL presentation, modulates the immunopeptidome, decreases HLA-B27 free heavy chain expression, and reduces IL-17A secretion. DG013A exhibits antiproliferative activity. DG013A can be used for research on autoimmune diseases and melanoma .
Cat. No.: HY-139907B
Purity: 99.60%
Target:
DG013A formate is a zinc-dependent M1-aminopeptidase inhibitor that exhibits inhibitory activity against ERAP1 (IC50 = 33 nM) and ERAP2 (IC50 = 11 nM). DG013A formate enhances SRHFLAFSFR epitope presentation, rescues GSW11 peptide neoantigen presentation, reduces SIINFEKL presentation, modulates the immunopeptidome, decreases HLA-B27 free heavy chain expression, and reduces IL-17A secretion. DG013A formate exhibits antiproliferative activity. DG013A formate can be used for research on autoimmune diseases and melanoma .
Cat. No.: HY-139907A
CAS No.: 2758817-06-8
Target:
Research Areas:
DG013B is an epimer of DG013A (HY-139907). DG013B has weak affinity for ERAP1 and ERAP2 and is often used as a negative control to study the binding properties of DG013A and its analogues to ERAP1 and ERAP2 .
Cat. No.: HY-139907C
Purity: 99.57%
Target:
Research Areas:
DG013B formate is an epimer of DG013A (HY-139907). DG013B formate has weak affinity for ERAP1 and ERAP2 and is often used as a negative control to study the binding properties of DG013A and its analogues to ERAP1 and ERAP2 .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
