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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
DHT/BSA
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "DHT/BSA" in MCE Product Catalog:
Cat. No.: HY-161566
Target:
Biochemical Assay Reagents Androgen Receptor Apoptosis Reactive Oxygen Species (ROS) Akt Caspase NADPH Oxidase
Research Areas:
DHT/BSA is an antigen-adjuvant conjugate of DHT (dihydrotestosterone) conjugated to bovine serum albumin (BSA) and a cell-impermeable membrane androgen receptor (mAR) agonist. DHT/BSA exacerbates neuronal apoptosis or induces cellular senescence under oxidative stress, and it rapidly inhibits estradiol synthesis and triggers reward and reinforcement behaviors in the central nervous system. DHT/BSA acts by specifically binding to mAR, triggering NOX/ROS generation, activating the NF-κB inflammatory pathway, or inhibiting signaling pathways such as Akt, without involving the classical nuclear translocation pathway. DHT/BSA can be used in research on Parkinson's disease and androgenetic alopecia .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
