2 Results for "

DPI-4452

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "DPI-4452" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P10761
CAS No.: 2941391-49-5
DPI-4452 is a CAIX-targeting cyclic peptide with a DOTA cage, and can be chelated with radionuclide for CAIX-expressing tumor PET-CT imaging and study. DPI-4452 specifically and selectively binds CAIX without interaction with an in vitro off-target receptor panel of 55 targets (IC50 for recombinant hCAIX: 130 nM). Radiolabeled DPI-4452 inhibits tumor growth in HT-29 and SK-RC-52 xenograft mouse models . DPI-4452 can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
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Cat. No.: HY-P10761A
NOTA-DPI-4452 TFA is a trifluoroacetate derivative with DPI-4452 (HY-P10761) as the parent peptide. DPI-4452 is a CAIX-targeting cyclic peptide with a DOTA cage that can chelate with radionuclides and is used to express CAIX tumors for PET-CT imaging and research .
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