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271 Results for "

DPPH radical

" in MedChemExpress (MCE) Product Catalog:

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DPPH

51 Publications Verification

Cat. No.: HY-112053

CAS No.: 1898-66-4

Purity: 98.77%

Synonyms: 2,2-Diphenyl-1-picrylhydrazyl

Target:

Reactive Oxygen Species (ROS) Free Radical Scavengers

Research Areas:

Metabolic Disease

DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that can be used to measure the radical scavenging activity of antioxidants. The odd electron of nitrogen atom in DPPH is reduced by receiving a hydrogen atom from antioxidants to the corresponding hydrazine. DPPH method may be utilized in aqueous and nonpolar organic solvents and can be used to examine both hydrophilic and lipophilic antioxidants .

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Pterostilbene

13 Cited Publications

Cat. No.: HY-N0828

CAS No.: 537-42-8

Category:

Monophenols Stilbenes Phenols Plants Other Families Extract Disease Research Fields Inflammation/Immunology

Target:

Free Radical Scavengers Autophagy

Pterostilbene is a stilbenoid isolated from blueberries and Pterocarpus marsupium . Shows anti-oxidant, anti-inflammatory, anti-carcinogenic, anti-diabetic and anti-obesity properties . Pterostilbene blocks ROS production , also exhibits inhibitory activity against various free radicals such as DPPH, ABTS, hydroxyl, superoxide and hydrogen peroxide .

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Famotidine

7 Cited Publications

Cat. No.: HY-B0377

CAS No.: 76824-35-6

Synonyms: MK-208

Target:

Histamine Receptor MMP Toll-like Receptor (TLR) ERK

Research Areas:

Infection Metabolic Disease Inflammation/Immunology

Famotidine (MK-208) is an orally active and highly selective histamine H2 receptor antagonist. It inhibits gastric acid secretion by blocking the Gs signaling pathway, and regulates intracellular cAMP and ERK pathways. Famotidine inhibits TLR3-mediated inflammatory pathways, and reduces the expression of various inflammatory mediators and interferon-related genes. Famotidine scavenges DPPH and nitric oxide free radicals, alleviates oxidative stress damage in gastric tissue, inhibits proMMP-9, improves vascular endothelial permeability, and restores the normal physiological functions of neutrophils and eosinophils. Famotidine crosses intestinal epithelial cells via facilitated diffusion and passive diffusion, blocks paracellular cation transport, and increases intestinal transepithelial electrical resistance. Famotidine reduces serum levels of transaminases and alkaline phosphatase, exerts analgesic effects and gastric protective effects simultaneously. Famotidine can be used in studies related to COVID-19, liver injury and acute gastric ulcer .

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