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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
DT9081
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "DT9081" in MCE Product Catalog:
Cat. No.: HY-189816
CAS No.: 2639645-80-8
Research Areas:
DT-9081 is an orally active and selective EP4 receptor antagonist, IC50 = 2.49 nM. DT-9081 blocks PGE2/EP4R-mediated cAMP signaling, counteracts EP4R-driven immunosuppression, and restores antitumor immunity. DT-9081 combined with anti-PD-1 antibody significantly improves tumor growth inhibition and animal survival in mouse tumor models. DT-9081 can be used in cancer-related research .
Cat. No.: HY-189816A
Research Areas:
DT-9081 hydrochloride is an orally active and selective EP4 receptor antagonist, IC50 = 2.49 nM. DT-9081 hydrochloride blocks PGE2/EP4R-mediated cAMP signaling, counteracts EP4R-driven immunosuppression, and restores antitumor immunity. DT-9081 hydrochloride combined with anti-PD-1 antibody significantly improves tumor growth inhibition and animal survival in mouse tumor models. DT-9081 hydrochloride can be used in cancer-related research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
