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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
DVL3
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "DVL3" in MCE Product Catalog:
Cat. No.: HY-RS04078
Target:
Research Areas:
DVL3 Human Pre-designed siRNA Set A contains three designed siRNAs for DVL3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS20721
Target:
Research Areas:
Dvl3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Dvl3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS27233
Target:
Research Areas:
Dvl3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Dvl3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-124784
CAS No.: 352544-59-3
Target:
Ligands for Target Protein for PROTAC Histone Methyltransferase Apoptosis Wnt β-catenin Bcr-Abl KLF
Research Areas:
PJ-68 is a selective PRMT5 inhibitor (IC50 = 517 nM). PJ-68 reduces KLF5 methylation, stability, and downstream target gene expression. PJ-68 induces Apoptosis, inhibits self-renewal capacity, blocks the Wnt/β-catenin signaling pathway by reducing DVL3 expression, and decreases BCR-ABL mRNA and protein levels. PJ-68 serves as a Ligand for Target Protein for PROTAC for the synthesis of PRMT5 PROTAC degraders, such as YZ-17 (HY-189213). PJ-68 inhibits the growth of basal-like breast cancer. PJ-68 prolongs the survival of CML mice. PJ-68 is used for research on basal-like breast cancer and chronic myeloid leukemia [3].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
