1 Result for "

DXR-IN-4

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "DXR-IN-4" in MCE Product Catalog:

Cat. No.: HY-170783
Target:  

Parasite

Research Areas:  

Infection

DXR-IN-4 (Compound 12a) is the inhibitor for 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR). DXR-IN-4 inhibits DXR in Plasmodium falciparum Pf DXR, Escherichia coli Ec DXR, and Mycobacterium tuberculosis Mt DXR with IC50s of 18, 4.9 and 89 nM, respectively. DXR-IN-4 exhibits antimalarial activity that inhibits P. falciparum strains 3D7 and Dd2 with IC50 of 11 μM and 12 μM .
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