50 Results for "

Domain III

" in MedChemExpress (MCE) Product Catalog:
Products (50)

50 Results for "Domain III" in MCE Product Catalog:

14
14 Publications Verification
Cat. No.: HY-P70664
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FNDC5; Fibronectin Type III Domain-Containing Protein 5; Fibronectin Type III Domain Containing 5; Fibronectin Type III Repeat-Containing Protein 2; FRCP2; Irisin
Species:  
Human Rat Mouse
Source:  
HEK293
loading...
    loading...
4
4 Cited Publications
Cat. No.: HY-P70665
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FNDC5; Fibronectin Type III Domain-Containing Protein 5; Fibronectin Type III Domain Containing 5; Fibronectin Type III Repeat-Containing Protein 2; FRCP2; Irisin
Species:  
Rat Mouse Human
Source:  
HEK293
loading...
    loading...
4
4 Cited Publications
Cat. No.: HY-P72534
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FNDC5; Fibronectin Type III Domain-Containing Protein 5; Fibronectin Type III Domain Containing 5; Fibronectin Type III Repeat-Containing Protein 2; FRCP2; Irisin
Species:  
Human Rat Mouse
Source:  
HEK293
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-P74566
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SEMA3A; Sema III; Prev. SEMAD; Semaphorin D; Hsema-I; Semaphorin L; Coll-1; Collapsin 1; SEMA1; Hsema-III; SemD; SEMAIII; Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A; COLL1; Semaphorin III; SEMAL; Semaphorin-3A;
Species:  
Mouse
Source:  
HEK293
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P71564
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SEMA3A; Sema III; Prev. SEMAD; Semaphorin D; Hsema-I; Semaphorin L; Coll-1; Collapsin 1; SEMA1; Hsema-III; SemD; SEMAIII; Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A; COLL1; Semaphorin III; SEMAL; Semaphorin-3A;
Species:  
Rat
Source:  
E. coli
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P76129
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Zika virus (ZIKV) (strain Zika SPH2015) ZIKV-E/Envelope protein (Domain III, His)
Species:  
Virus
Source:  
HEK293
loading...
    loading...
Cat. No.: HY-P99155
CAS No.: 667901-13-5
Synonyms: 2F8; HUMAX-EGFR

Target:  

EGFR

Research Areas:  

Cancer

Zalutumumab is a high affinity, completely human IgG1 monoclonal antibody targeting EGFR. Zalutumumab binds to domain III of the EGF receptor and acts by blocking the binding of EGF and by sterically interfering with the active conformation of the receptor. Zalutumumab binds with IgG and its Fab fragment with EC50s of 7 and 19 nM, respectively. Zalutumumab can be used for the research of cancer .
loading...
    loading...
Cat. No.: HY-138053
CAS No.: 92989-99-6
Synonyms: Ristomycin III
Target:  

Antibiotic

Research Areas:  

Cardiovascular Disease Infection

Ristocetin A (sulfate) (Ristomycin III) is a glycopeptide antibiotic that binds to von Willebrand factor (VWF) and bacterial cell wall components. Ristocetin A (sulfate) interferes with the biosynthesis of bacterial peptidoglycan by inhibiting transpeptidation. As an inducer of platelet adhesion and aggregation, Ristocetin A (sulfate) drives conformational changes by binding to the A1 domain of VWF, thereby activating downstream signaling pathways and promoting cytoskeletal rearrangement. Ristocetin A (sulfate) not only enhances platelet adhesion and spreading on immobilized VWF, but also induces the formation of asymmetric dimers with anticooperativity between platelets and plasma VWF. Ristocetin A (sulfate) is widely used in studies related to thromboembolic diseases and bacterial infections .
loading...
    loading...
Cat. No.: HY-NP131
Research Areas:  

Cancer

Recombinant Humanized Type III Collagen 10.4kDa is a novel biomaterial that have anticancer effects. Recombinant Humanized Type III Collagen 10.4kDa activates discoidin domain receptor 1 (DDR1), and thus inhibits autophagy, proliferation, and migration of cancer cells, and induces apoptosis .
loading...
    loading...
Cat. No.: HY-148366
Purity:  98.99%
Research Areas:  

Cancer

NecroIr2 is an iridium(III) complex, serves as necroptosis inducers in Cisplatin (HY-17394)-resistant lung cancer cells (A549R). NecroIr2 selectively accumulates in mitochondria, leading to oxidative stress and loss of mitochondrial membrane potential (MMP). NecroIr2 activates receptor-interacting serine-threonine kinase 3 (RIPK3) and mixed lineage kinase domain-like pseudokinase (MLKL), and regulates CDK4 expression .
loading...
    loading...
Cat. No.: HY-P99155A
CAS No.: 667901-13-5

Target:  

EGFR

Research Areas:  

Cancer

Zalutumumab (powder) is a high affinity, completely human IgG1 monoclonal antibody targeting EGFR. Zalutumumab (powder) binds to domain III of the EGF receptor and acts by blocking the binding of EGF and by sterically interfering with the active conformation of the receptor. Zalutumumab (powder) binds with IgG and its Fab fragment with EC50s of 7 and 19 nM, respectively. Zalutumumab (powder) can be used for the research of cancer .
loading...
    loading...
Cat. No.: HY-P991779

Target:  

EGFR

Research Areas:  

Cancer

Anti-Mouse/Human/Canine HER2 (domain III) Antibody (H2Mab-19) reacts with domain III of human and canine HER2. Anti-Mouse/Human/Canine HER2 (domain III) Antibody (H2Mab-19) exerts antitumor activity in mouse oral cancer xenografts. Recommend Isotype Controls: Mouse IgG2b kappa, Isotype Control (HY-P99982) .
loading...
    loading...
Cat. No.: HY-P99306
CAS No.: 1310460-86-6
Synonyms: DS 1024; Zatuximab

Target:  

EGFR

Research Areas:  

Cancer

Modotuximab (DS 1024) is an IgG1κ-type chimeric antibody targeting human EGFR protein. Modotuximab binds non-overlapping epitopes on domain III of EGFR, a domain that is intact in EGFRvIII. Modotuximab has antitumor activity in vivo .
loading...
    loading...
Cat. No.: HY-P1816
CAS No.: 136466-51-8
Target:  

Integrin

Research Areas:  

Cancer

The connecting segment 1 (CS-1) is a cell attachment domain located in the type III homology connecting segment (IIICS) of fibronectin. Fibronectin CS1 Peptide lacks the Arg-Gly-Asp-containing domain, actively inhibits tumor metastases in spontaneous and experimental metastasis models .
loading...
    loading...
Cat. No.: HY-150683
CAS No.: 3031654-46-0
Research Areas:  

Cancer

NC-III-49-1 is a potent bivalent bromodomain and extraterminal domain (BET) inhibitor. NC-III-49-1 shows binding potential for BRD4-1, BRD4-2, BRD4-T, BRDT-1, BRDT-2, BRDT-T with Kd values of 0.095, 0.32, 0.29, 0.089, 5.5, 0.058 nM, respectively. NC-III-49-1 shows antiproliferative activity. NC-III-49-1 decreases the expression of c-Myc .
loading...
    loading...
Cat. No.: HY-E70834
Target:  

JAK

Research Areas:  

Cancer

JAK1 is a non-receptor tyrosine kinase that plays a critical role in cell signaling via type I/II cytokines and interferons (IFNs). JAK1(JH1) is a kinase domain. JAK1(JH1) Recombinant Human Active Protein Kinase is a recombinant JAK1(JH1) protein that can be used to study JAK1(JH1)-related functions .
loading...
    loading...
Cat. No.: HY-P991784

Target:  

EGFR

Research Areas:  

Others

Anti-Mouse/Human EGFR (domain III) Antibody (EMab-88) reacts with domain III of the mouse and human EGFR. Recommend Isotype Controls: Mouse IgG1 kappa, Isotype Control (HY-P99977).
loading...
    loading...
Cat. No.: HY-P73535
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Zika virus (ZIKV) (strain Zika SPH2015) E/Envelope protein (Domain III, His)
Species:  
Virus
Source:  
P. pastoris
loading...
    loading...
Cat. No.: HY-P76935
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FNDC4; Fibronectin Type III Domain-Containing Protein 4; Fibronectin Type III Domain Containing 4; Fibronectin Type III Repeat-Containing Protein 1; FRCP1; FLJ22362
Species:  
Human
Source:  
HEK293
loading...
    loading...
Cat. No.: HY-P71674
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SEMA3F; Semaphorin IV; Semaphorin 3F; Sema IV; SEMAK; Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, 3F; Sema4; Semaphorin III/F; Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3F; Sema III/F; Semaphorin-3F; SEMA-IV
Species:  
Human
Source:  
HEK293
loading...
    loading...