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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
982 Results for "
Drug Derivative
" in MedChemExpress (MCE) Product Catalog:
Products (982)
982 Results for "Drug Derivative" in MCE Product Catalog:
63
63 Publications Verification
Synonyms: MMAE; SGD-1010
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Monomethyl auristatin E (MMAE; SGD-1010) is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) to treat several different cancer types.
35
35 Cited Publications
Synonyms: MC-GGFG-DXD
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Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing Trastuzumab deruxtecan (HY-138298A) and Patritumab deruxtecan (HY-P99813) .
14
14 Cited Publications
Synonyms: Exatecan Derivative for ADC
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DXd (Exatecan derivative for ADC) is a potent DNA topoisomerase I inhibitor, with an IC50 of 0.31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a).
8
8 Cited Publications
Cat. No.: HY-P9921A
CAS No.: 1018448-65-1
Synonyms: Ado-Trastuzumab emtansine (solution) ; PRO132365 (solution) ; T-DM 1 (solution)
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Trastuzumab emtansine (Ado-Trastuzumab emtansine) is an antibody-drug conjugate (ADC) that incorporates the HER2-targeted antitumor properties of trastuzumab with the cytotoxic activity of the microtubule-inhibitory agent DM1 (derivative of maytansine), and the drug-linker conjugate for ADC is SMCC-DM1 (HY-101070). Trastuzumab emtansine can be used for the research of advanced breast cancer .
3
3 Cited Publications
Cat. No.: HY-W441014
DSPE-PEG2000-NHS is a PEG-modified phospholipid derivative that can be used to prepare liposomes. DSPE-PEG2000-NHS is commonly employed as a linker molecule for the surface modification of liposomes to confer targeting capabilities. DSPE-PEG2000-NHS can be used in the study of drug delivery .
2
2 Cited Publications
Cat. No.: HY-170706
CAS No.: 1445832-74-5
DSPE-PEG2000-NHCO-COOH is a pegylated derivative of 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (HY-112530) . DSPE-PEG2000-NHCO-COOH can form micelles for targeted drug delivery .
1
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1
1 Cited Publications
Cat. No.: HY-W007466
CAS No.: 504-02-9
1
1
1 Cited Publications
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DBCO-NHS ester 2 is a cleavable linker that is used for making antibody-drug conjugate (ADC). DBCO-NHS ester 2 is a derivative of Dibenzylcyclooctyne (DBCO) used in copper-free click chemistry[1]. DBCO-NHS ester 2 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
1
1 Cited Publications
Cat. No.: HY-112624I
CAS No.: 9004-54-0
Synonyms: Dextran 3; Dextran D3; Dextran T3(MW 2400-3600)
1
Category:
Olax imbricata Ketones, Aldehydes, Acids Other Diseases Plants Olacaceae Extract Disease Research Fields
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1
1 Cited Publications
Cat. No.: HY-W010712
CAS No.: 109425-51-6
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Cat. No.: HY-W015503
CAS No.: 1198-37-4
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4-Methylquinaldine is a quinoline derivative and can be used as a drug intermediate.
Cat. No.: HY-W002864
CAS No.: 6311-35-9
Cat. No.: HY-W738358
CAS No.: 6001-93-0
Chlorproguanil (hydrochloride) is an antimalarial drug. Chlorproguanil (hydrochloride) is a dichloro-derivative of chloroguanide .
Cat. No.: HY-129771
CAS No.: 676487-42-6
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3-Bromomethcathinone (3-BMC) hydrochloride is a drug derivative.
Cat. No.: HY-168403
CAS No.: 2748304-64-3
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3',4'-Trimethylene-α-pyrrolidinohexanophenone hydrochloride is structurally categorized as a drug derivative.
Cat. No.: HY-W076900
CAS No.: 1577-22-6
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5-Hexenoic acid is a carboxylic acid derivative and can be used as a drug intermediate in the production of various compounds.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
