1274 Results for "

E. c.

" in MedChemExpress (MCE) Product Catalog:
Products (1274)

1274 Results for "E. c." in MCE Product Catalog:

109
Vemurafenib
Vemurafenib
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109 Publications Verification
Cat. No.: HY-12057
CAS No.: 918504-65-1
Purity:  99.85%
Synonyms: PLX4032; RG7204; RO5185426
Target:  

Raf Autophagy

Research Areas:  

Cancer

Vemurafenib (PLX4032) is a first-in-class, selective, potent inhibitor of B-RAF kinase, with IC50s of 31 and 48 nM for RAF V600E and c-RAF-1, respectively . Vemurafenib induces cell autophagy .
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96
Aloxistatin
Aloxistatin
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96 Cited Publications
Cat. No.: HY-100229
CAS No.: 88321-09-9
Purity:  99.55%
Synonyms: E64d; E64c ethyl ester
Target:  

Cathepsin SARS-CoV

Research Areas:  

Neurological Disease

Aloxistatin (E64d) is a cell-permeable and irreversible broad-spectrum cysteine protease inhibitor. Aloxistatin (E64d) exhibits entry-blocking effect for MERS-CoV.
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90
Dabrafenib Mesylate
Dabrafenib Mesylate
0 Images
90 Cited Publications
Cat. No.: HY-14660A
CAS No.: 1195768-06-9
Purity:  99.95%
Synonyms: GSK2118436 Mesylate; GSK 2118436B
Target:  

Raf

Research Areas:  

Cancer

Dabrafenib Mesylate is a potent and selective Raf kinase inhibitor with IC50s of 0.6 and 5.0 nM for Raf V600E and c-Raf, respectively.
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90
Dabrafenib
Dabrafenib
0 Images
90 Cited Publications
Cat. No.: HY-14660
CAS No.: 1195765-45-7
Purity:  99.94%
Synonyms: GSK2118436A; GSK2118436
Target:  

Raf CDK

Research Areas:  

Cancer

Dabrafenib (GSK2118436A) is an ATP-competitive inhibitor of Raf with IC50s of 5 nM and 0.6 nM for C-Raf and B-Raf V600E, respectively .
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35
Entrectinib
Entrectinib
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35 Cited Publications
Cat. No.: HY-12678
CAS No.: 1108743-60-7
Purity:  99.79%
Synonyms: NMS-E628; RXDX-101
Target:  

ROS Kinase Trk Receptor Anaplastic lymphoma kinase (ALK) Autophagy

Research Areas:  

Cancer

Entrectinib (NMS-E628) is an orally active, BBB-penetrated and centrally active inhibitor of TrkA/B/C, ROS1 and ALK, with IC50 values of 1, 3, 5, 12 and 7 nM, respectively. Entrectinib induces apoptosis and cycle arrest in cancer cells, has antitumor activity, and attenuates bleomycin-induced lung fibrosis in mice .
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22
RNase Inhibitor
RNase Inhibitor
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22 Cited Publications
Cat. No.: HY-K1033

RNase Inhibitor is a 50 kDa recombinant protein expressed in E.coli, and can specifically inhibit RNase A, B and C. The 10 KU volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

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22
JIB-04
JIB-04
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22 Cited Publications
Cat. No.: HY-13953
CAS No.: 199596-05-9
Purity:  98.29%
Target:  

Histone Demethylase Apoptosis

Research Areas:  

Cancer

JIB-04 is a pan-selective Jumonji histone demethylase inihibitor with IC50s of 230, 340, 855, 445, 435, 1100, and 290 nM for JARID1A, JMJD2E, JMJD3, JMJD2A, JMJD2B, JMJD2C, and JMJD2D, respectively.
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22
Guggulsterone
Guggulsterone
0 Images
22 Cited Publications
Cat. No.: HY-107738
CAS No.: 95975-55-6
Purity:  99.81%
Synonyms: Z/E-Guggulsterone
Category:  

Triterpenes Terpenoids Burseraceae Extract Plants Disease Research Fields 500 - Internal Server Error | MedChemExpress

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