1 Result for "

E0924G

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "E0924G" in MCE Product Catalog:

Cat. No.: HY-168336
CAS No.: 2909474-29-7
Target:  

PPAR

Research Areas:  

Metabolic Disease

E0924G is an orally active activator for PPARδ with EC50 of 2.82 μM. E0924G promotes the upregulation of osteoprotegerin (OPG) with an EC50 of 0.29 μM. E0924G reduces RANKL-induced osteoclast differentiation and inhibites F-actin ring formation in RAW264.7 macrophages. E0924G regulates the bone density and bone loss in ovariectomized (OVX) and age-related osteoporosis models .
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