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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
E17K
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "E17K" in MCE Product Catalog:
21
Miransertib (ARQ-092) is a potent, orally active, selective and allosteric Akt inhibitor with IC50s of 2.7 nM, 14 nM and 8.1 nM for Akt1, Akt2, Akt3, respectively. Miransertib is also a potent the AKT1-E17K mutant protein inhibitor and has the potential for PI3K/AKT-driven tumors and Proteus syndrome research . Miransertib is effective against Leishmania .
21
Miransertib hydrochloride (ARQ-092 hydrochloride) is a potent, orally active, selective and allosteric Akt inhibitor with IC50s of 2.7 nM, 14 nM and 8.1 nM for Akt1, Akt2, Akt3, respectively. Miransertib hydrochloride is also a potent the AKT1-E17K mutant protein inhibitor and has the potential for PI3K/AKT-driven tumors and Proteus syndrome research . Miransertib hydrochloride is effective against Leishmania .
Cat. No.: HY-176299
CAS No.: 3034255-93-8
Tanerasertib (Compound 456) is an AKT1 inhibitor, targerting to AKT1 E17K with the EC50 of 15-60 nM. Tanerasertib can be used in the study of cancer .
Cat. No.: HY-E70786
AKT is the oncogenic protein kinase that regulates essential cellular functions such as migration, proliferation, differentiation, apoptosis, and metabolism. Mammalian cells are characterized by the expression of three different Akt isoforms, Akt1, Akt2, and Akt3. AKT1 E17K is a mutant of AKT1. AKT1 E17K Recombinant Human Active Protein Kinase is obtained by expressing AKT1 E17K proteins .
Cat. No.: HY-19719B
CAS No.: 1817727-88-0
Synonyms: ARQ-092 mesylate
Miransertib (ARQ-092) mesylate is a potent, orally active, selective and allosteric Akt inhibitor with IC50s of 2.7 nM, 14 nM and 8.1 nM for Akt1, Akt2, Akt3, respectively. Miransertib mesylate is also a potent the AKT1-E17K mutant protein inhibitor and has the potential for PI3K/AKT-driven tumors and Proteus syndrome research . Miransertib mesylate is effective against Leishmania .
Cat. No.: HY-P705728
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: AKT2; Non-Specific Serine/Threonine Protein Kinase; AKT Serine/Threonine Kinase 2; Murine Thymoma Viral (V-Akt) Homolog-2; V-Akt Murine Thymoma Viral Oncogene Homolog 2; Rac Protein Kinase Beta; RAC-Beta Serine/Threonine-Protein Kinase; RAC Protein Kinase
Species:
Human
Source:
sf9 insect cells
Cat. No.: HY-P705729
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: AKT3; V-Akt Murine Thymoma Viral Oncogene Homolog 3; AKT Serine/Threonine Kinase 3; Non-Specific Serine/Threonine Protein Kinase; PKBG; RAC-Gamma Serine/Threonine Protein Kinase; RAC-Gamma; Protein Kinase B, Gamma; PRKBG; Protein Kinase B Gamma; RAC-Gamma
Species:
Human
Source:
sf9 insect cells
Cat. No.: HY-P705727
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: AKT1; Protein Kinase B; AKT Serine/Threonine Kinase 1; PKB Alpha; RAC; V-Akt Murine Thymoma Viral Oncogene-Like Protein 1 Isoform 2; PKB; V-Akt Murine Thymoma Viral Oncogene-Like Protein 1; RAC-Alpha Serine/Threonine-Protein Kinase; Non-Specific Serine/Th
Species:
Human
Source:
sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
