2 Results for "

E52

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "E52" in MCE Product Catalog:

Cat. No.: HY-W014109
CAS No.: 69304-49-0
Synonyms: (E)-5-(2-Bromovinyl)uracil; BVU
Target:  

DNA/RNA Synthesis

Research Areas:  

Infection

(E)-5-(2-Bromovinyl)uracil (BVU) is a pyrimidine base and an inactive metabolite of the antiviral agents sorivudine and (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) that may be regenerated to BVDU in vivo. BVU irreversibly inactivates dihydropyrimidine dehydrogenase (DPD) in an NADPH-dependent manner. It enhances the efficacy of the chemotherapeutic agent and DPD substrate 5-fluorouracil (HY-90006) in a P388 murine leukemia model when administered at a dose of 200 μmol/kg, increasing survival time.
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Cat. No.: HY-W998842
CAS No.: 156421-74-8
Target:  

MOFs

Research Areas:  

Others

(E)-5-(2-Carboxyvinyl)furan-2-carboxylic acid is a metal-organic framework (MOF).
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