country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

3 Results for "

ECA109

" in MedChemExpress (MCE) Product Catalog:

Products (3)

Sort by :

Categories

By Targets

Products

P-gp inhibitor 29

Cat. No.: HY-173401

CAS No.: 3082344-99-5

Target:

P-glycoprotein

Research Areas:

Cancer

P-gp inhibitor 29 (41) is a highly potent P-gp inhibitor and apoptosis inducer, with an IC₅₀ of 8.9 nM in Eca109/VCR cells. P-gp inhibitor 29 (41) can be used in the research for Esophageal Cancer .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

PI3K/mTOR-IN-19

Cat. No.: HY-179155

Target:

PI3K mTOR Apoptosis Bcl-2 Family MDM-2/p53 Telomerase Mitochondrial Metabolism

Research Areas:

Inflammation/Immunology Cancer

PI3K/mTOR-IN-19 is an orally active, potent, selective PI3K (IC₅₀ = 4.23 nM) and mTOR (IC₅₀ = 2.3 nM) inhibitor. PI3K/mTOR-IN-19 significantly inhibits Eca109 cell viability and induces apoptosis. PI3K/mTOR-IN-19 causes G0/G1 cell cycle arrest, decreased mitochondrial membrane potential, and demonstrates marked telomerase inhibitory activity. PI3K/mTOR-IN-19 modulates the expression of key apoptotic regulators (Bcl-2, Bax, and p53) and downregulates the PI3K/Akt/mTOR signaling pathway. PI3K/mTOR-IN-19 can be used for the study of esophageal cancer .

Compare