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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
EMD 1214063
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "EMD 1214063" in MCE Product Catalog:
10
Target:
Research Areas:
Tepotinib (EMD-1214063) is an orally active and highly selective, reversible, ATP-competitive c-Met inhibitor with an IC50 of 3 nM, >200-fold selective for c-Met than IRAK4, TrkA, Axl, IRAK1, and Mer. Tepotinib inhibits c-Met phosphorylation and induces autophagy. Tepotinib has antitumor effects .
Cat. No.: HY-14721R
CAS No.: 1100598-32-0
Synonyms: EMD-1214063 (Standard)
Target:
Research Areas:
Tepotinib (Standard) is the analytical standard of Tepotinib. This product is intended for research and analytical applications. Tepotinib (EMD-1214063) is an orally active and highly selective, reversible, ATP-competitive c-Met inhibitor with an IC50 of 3 nM, >200-fold selective for c-Met than IRAK4, TrkA, Axl, IRAK1, and Mer. Tepotinib inhibits c-Met phosphorylation. Tepotinib has antitumor effects .
Cat. No.: HY-14721A
CAS No.: 1103508-80-0
Synonyms: EMD-1214063 hydrochloride
Target:
Research Areas:
Tepotinib (EMD-1214063) hydrochloride is an orally active and highly selective, reversible, ATP-competitive c-Met inhibitor with an IC50 of 3 nM, >200-fold selective for c-Met than IRAK4, TrkA, Axl, IRAK1, and Mer. Tepotinib hydrochloride inhibits c-Met phosphorylation and induces autophagy. Tepotinib hydrochloride has antitumor effects .
Cat. No.: HY-14721S1
Synonyms: EMD-1214063-d3
Research Areas:
Tepotinib-d3 (EMD-1214063-d3) is the deuterated-labeled Tepotinib (HY-14721). Tepotinib (EMD-1214063) is an orally active and highly selective, reversible, ATP-competitive c-Met inhibitor with an IC50 of 3 nM, >200-fold selective for c-Met than IRAK4, TrkA, Axl, IRAK1, and Mer. Tepotinib inhibits c-Met phosphorylation and induces autophagy. Tepotinib has antitumor effects .
Cat. No.: HY-14721S
Synonyms: EMD-1214063-13C,d3
Research Areas:
Tepotinib- 13C,d3 (EMD-1214063- 13C,d3) is the 13C, deuterated-labeled Tepotinib (HY-14721). Tepotinib (EMD-1214063) is an orally active and highly selective, reversible, ATP-competitive c-Met inhibitor with an IC50 of 3 nM, >200-fold selective for c-Met than IRAK4, TrkA, Axl, IRAK1, and Mer. Tepotinib inhibits c-Met phosphorylation and induces autophagy. Tepotinib has antitumor effects .
Cat. No.: HY-N8425S
Target:
Research Areas:
Tepotinib-d3 (EMD-1214063-d3) is the deuterated-labeled Tepotinib (HY-14721). Tepotinib (EMD-1214063) is an orally active and highly selective, reversible, ATP-competitive c-Met inhibitor with an IC50 of 3 nM, >200-fold selective for c-Met than IRAK4, TrkA, Axl, IRAK1, and Mer. Tepotinib inhibits c-Met phosphorylation and induces autophagy. Tepotinib has antitumor effects .
Cat. No.: HY-14721S2
Synonyms: EMD-1214063-d5
Research Areas:
Octacosanoic acid-d35 is the deuterated-labeled Octacosanoic acid. Octacosanoic acid (Montanic acid) is a long-chain saturated fatty acid and a major component of sugarcane wax mixture and D-003. Octacosanoic acid can be formed in the liver from Octacosanol (HY-N6811) and inhibits nitric oxide (NO) production in LPS-activated macrophages and LPS-induced splenic lymphocyte proliferation. Octacosanoic acid can be used in anti-inflammatory and lipid metabolism-related research.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
