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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
59 Results for "
ESR spectroscopy
" in MedChemExpress (MCE) Product Catalog:
Products (59)
59 Results for "ESR spectroscopy" in MCE Product Catalog:
7
7 Publications Verification
Synonyms: GDC-9545; RG6171
Target:
Research Areas:
Giredestrant (GDC-9545) is an orally active, full, selective Estrogen receptor α (ERα) degrader and antagonist with a DC50 of 0.03 nM. Giredestrant promotes the degradation of ERα protein, including the ESR1 Y537S mutant ERα. Giredestrant reduces uterine wet weight in immature rats and induces a low cuboidal phenotype in their endometrial epithelium. Giredestrant induces tumor regression in both ESR1 Y537S mutant and wild-type ERα tumor models. Giredestrant can be used for the research of ER + breast cancer .
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2
1
1 Cited Publications
Research Areas:
VT02956 is a LATS inhibitor (IC50: 0.76 nM for LATS1, 0.52 nM for LATS2). VT02956 targets the Hippo pathway. VT02956 inhibits ESR1 expression and growth of ER+ breast cancer cell lines and patient-derived tumor organoids . VT02956 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
1
1 Cited Publications
Cat. No.: HY-P70248
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ESR1; Estrogen Receptor Alpha Delta 4*,5,6,7*/654 Isoform; Prev. ESR; Estrogen Receptor Alpha 3*,4,5,6,7,8*/1032 Isoform; ER-Alpha; Estrogen Receptor Alpha 3*,4,5,6,7,8*/1068 Isoform; ER; Estrogen Receptor Alpha 3*,4,5,6,7,8*/984 Isoform; Nuclear Receptor Subfamily 3 Group A Member 1; Hippocampal Estrogen Receptor Alpha Isoform TADDI; Estradiol Receptor; Estrogen Receptor Alpha 2*,3,4,5,6,7*,8* Isoform; NR3A1; Estrogen Receptor Alpha 3*,4,5,6,7*/765 Isoform; Estrogen Receptor; Estrogen Receptor Alpha 3*,4,5,6,7*/822 Isoform; Era; Estrogen Receptor Alpha Delta 3*4,5*,7 Isoform; Oestrogen Receptor Alpha; Estrogen Receptor Alpha Delta 4,5,6,7 Isoform; Estrogen Receptor Alpha; Estrogen Receptor Alpha Delta 3*4*,7 Isoform; E2 Receptor Alpha; Estrogen Receptor Alpha E1-N2-E2-1-2 Variant; Estrogen Receptor Alpha Delta 2*,3,4,5,6,7*/834 Hypothalamic Isoform; Estrogen Receptor Alpha Delta 4,5,7 Isoform; Estrogen Receptor Alpha Delta 3*,4,5,6,7*/775 Hypothalamic Isoform; Estrogen Receptor Alpha Delta 4 +49 Isoform; Estrogen Receptor Alpha Delta 1*,2,3*/663 Choroid Plexus Isoform; Estrogen Receptor Alpha E1-N1-E2-1 Variant; Estrogen Receptor Alpha Delta 4,7*,8*/581 Hypothalamic Isoform; Estrogen Receptor Alpha E1-N2-E2-2 Variant; Estrogen Receptor Alpha Delta 4*,5,6*/481 Hypothalamic Isoform; Estrogen Receptor Alpha Delta 6,7 Isoform; Estrogen Receptor Alpha Delta 3*,4,5,6,7*, 8*/912 Isoform; Estrogen Receptor Alpha E1-E2-1-2 Variant; Estrogen Receptor Alpha Delta 3*,4,5,6,7*,8*/941 Isoform; Estrogen Receptor Alpha E1-E2-2 Variant; Estrogen Receptor Alpha Delta 3*,4,5,6,7,8*/1029 Isoform; Estrogen Receptor Alpha Splice Variant; Estrogen Receptor Alpha Delta 3*,4,5,6,7*/819-2 Isoform; Estrogen Receptor Alpha E1-1-2 Variant; Estrogen Receptor Alpha Delta 3*,4,5,6,7,8*/969 Isoform; Estrogen Receptor Alpha E1-N2-E2-1-2; Estrogen Receptor Alpha Delta 3*,4,5,6,7,8*/984 Isoform; Estrogen Receptor Alpha E1-2 Variant; Estrogen Receptor Alpha Delta 2*,3,4,5,6,7*/963 Isoform; Estrogen Receptor Alpha E1-E2-1-2; Estrogen Receptor Alpha Superior Frontal Gyrus Isoform; Estrogen Nuclear Receptor Alpha; Estrogen Receptor Alpha Delta 4*,5,6,7,8*/918 Isoform; Estrogen Receptor Protein; Estrogen Receptor Alpha Delta 4*,5,6,7,8*/885 Isoform; Alternative Protein ESR1; Estrogen Receptor Alpha Delta 4*,5,6,7,8*/901 Isoform; ESTRR; Estrogen Receptor Alpha Delta 4*,5,6,7*/633 Isoform; ESRA; Estrogen Receptor 1; Estrogen Receptor Alpha Delta 2*,3,4,5,6,7 Isoform
Species:
Human
Source:
E. coli
Cat. No.: HY-W016371
CAS No.: 33216-52-3
Synonyms: 3,4,5-threechlorine pyridine
Cat. No.: HY-W034674
CAS No.: 1470-61-7
Synonyms: Silver(1+) diethyldithiocarbamate
Cat. No.: HY-W016510
CAS No.: 515-42-4
Cat. No.: HY-163650
CAS No.: 252950-56-4
Target:
Research Areas:
DTPD-Q is an antioxidant and an oxidative derivative of methylbenzenesulfonyl-p-phenylenediamine DTPD. DTPD-Q is a molecule that binds to AKT1 and ESR1, with high binding affinity to core targets associated with male infertility and its subtypes. DTPD-Q can be used in studies related to male infertility .
Cat. No.: HY-N1508
CAS No.: 78285-90-2
Cat. No.: HY-RS04529
Target:
Research Areas:
ESR1 Human Pre-designed siRNA Set A contains three designed siRNAs for ESR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS04530
Target:
Research Areas:
Esr1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Esr1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-W033573
CAS No.: 15305-72-3
Target:
Research Areas:
Hexaammineruthenium(II) chloride is a non-corrosive redox probe. Hexaammineruthenium(II) chloride avoids gold electrode corrosion and degradation to enable stable electrochemical impedance spectroscopy measurements. Hexaammineruthenium(II) chloride supports detection of human-IgG with a defined diagnostic concentration range .
Cat. No.: HY-W011607
CAS No.: 16305-75-2
Target:
Research Areas:
L-Alanyl-L-tryptophan is a dipeptide formed from L-alanyl and L-tryptophan, and is also a metabolite. L-Alanyl-L-tryptophan can be adsorbated on the surface of gold nanoparticles, and the Raman signal can be enhanced by SERS technology to obtain the enhanced Raman spectroscopy .
Target:
Research Areas:
(6E)-SR 11302 is a E-isomer of SR 11302. SR 11302 is an activator protein-1 (AP-1) transcription factor inhibitor. SR 11302 is a retinoid that specifically inhibits AP-1 activity without activating the transcription of retinoic acid response element (RARE) .
Cat. No.: HY-D1993
Target:
Research Areas:
4-Methylbenzyl cyanide is an organic chemical probe used to study intramolecular rotation properties. 4-Methylbenzyl cyanide is promising for research of NMR spectroscopy and physical chemistry research on molecular dynamics .
Cat. No.: HY-135903
CAS No.: 2407529-33-1
Synonyms: GDC-9545 tartrate; RG6171 tartrate
Target:
Giredestrant tartrate (GDC-9545 tartrate) is an orally active, full, selective Estrogen receptor α (ERα) degrader and antagonist with a DC50 of 0.03 nM. Giredestrant tartrate promotes the degradation of ERα protein, including the ESR1 Y537S mutant ERα. Giredestrant tartrate reduces uterine wet weight in immature rats and induces a low cuboidal phenotype in their endometrial epithelium. Giredestrant tartrate induces tumor regression in both ESR1 Y537S mutant and wild-type ERα tumor models. Giredestrant tartrate can be used for the research of ER + breast cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
