39 Results for "

Environmental Pollutants

" in MedChemExpress (MCE) Product Catalog:
Products (39)

39 Results for "Environmental Pollutants" in MCE Product Catalog:

12
12 Cited Publications
Cat. No.: HY-153169
CAS No.: 2754428-18-5
Purity:  99.30%
Synonyms: 6PPD-Quinone
6PPD-Q (6PPD-Quinone) is an environmental pollutant that can be detected in human urine and is widely present in the environment. 6PPD-Q targets and binds to CNR2, CNR1, AA2AR, LCAT, and TRPA1, with CNR2 exhibiting the highest binding affinity, potentially acting as a CNR2 receptor agonist to activate cannabinoid receptors. 6PPD-Q induces intestinal inflammation and barrier damage by disrupting mitochondrial function, reducing neuronal glycolysis metabolites and TCA cycle intermediates, and exacerbating α-synuclein (α-syn) aggregation. 6PPD-Q is applicable in research on environmental toxicology, neurodegenerative diseases, and inflammation-related disorders .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W754777
CAS No.: 68054-73-9
Research Areas:  

Others

IPPD-Q is a p-phenylenediamine quinone and also Environmental pollutant. IPPD-Q can be present in tires, fine particulate matter and urban water bodies. IPPD-Q increases the activities of antioxidant enzymes (SOD, CAT), alters photosynthesis and energy metabolism pathways, and changes gene expression and metabolic profiles. IPPD-Q exhibits phytotoxic effects. IPPD-Q shows acute toxicity to zebrafish embryos and reduces their survival rate .
loading...
    loading...
Cat. No.: HY-W051271
CAS No.: 13463-67-7
Synonyms: Titanium dioxide
Titanium(IV) oxide is a photosensitizer and photocatalyst. Titanium(IV) oxide can be used as a pharmaceutical excipient such as a flow aid, coating agent, sunscreen, colorant, etc. Pharmaceutical excipients or pharmaceutical excipients refer to other chemical substances used in the pharmaceutical process other than the drug ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations that can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism and elimination (ADME) process of co-administered drugs. Titanium(IV) oxide can use light energy to generate electron-hole pairs to degrade pollutants. Photons excite electrons in TiO2 to generate active oxygen species (such as ·OH and ·O2 -), thereby oxidizing and mineralizing pollutants such as organic compounds and heavy metals. TiO2 can be used in the research of environmental remediation fields such as water treatment, air purification and self-cleaning materials .
loading...
    loading...
Cat. No.: HY-E70387
CAS No.: 42613-30-9
Target:  

Endogenous Metabolite

Research Areas:  

Others

Ligninase is a general term for extracellular heme-containing peroxidases produced by Phanerochaete chrysosporium. Ligninase can catalyze lignin degradation. Ligninase can be used in waste treatment and detoxification of environmental pollutants .
loading...
    loading...
Cat. No.: HY-21197
CAS No.: 375-85-9
Synonyms: Perfluoroheptanoic acid; Tridecafluoroheptanoic acid; PFHpA
Perfluoroenanthic acid (Perfluoroheptanoic acid) is a kind of perfluoroalkyl carboxylic acid organic pollutant. Perfluoroenanthic acid has environmental persistence and bioaccumulation, and exposure can occur via oral, dermal and other routes. Perfluoroenanthic acid exhibits reproductive toxicity, neurotoxicity, hepatotoxicity, immunotoxicity and endocrine-disrupting effects. Perfluoroenanthic acid exerts definite adverse effects on development, spermatogenesis, neuronal activity and liver tissue .
loading...
    loading...
Cat. No.: HY-W017960
CAS No.: 1149-23-1
Synonyms: Et-HE; 1,4-DHP
Diludine (BNP-7787) is an orally effective feed additive. Diludine reduces the activity of G6PD and increases the level of superoxide dismutase (SOD). Diludine reduces the mutagenic effect of environmental pollutants, protects parental reproductive systems and improves offspring quality. Diludine is mainly applied during the transition period of dairy cows to increase milk yield and milk fat content, and improve health status during parturition. Diludine can be used in animal feeding research .
loading...
    loading...
Cat. No.: HY-119725
CAS No.: 116-29-0
Purity:  99.71%
Research Areas:  

Infection

Tetradifon is a broad-spectrum organochlorine insecticide and an inhibitor of the mitochondrial oligomycin sensitivity conferring protein (OSCP), which can be used to control a variety of mites. Tetradifon inhibits energy-related activities such as ADP-stimulated respiration, DNP and Mg 2+-stimulated ATPase, with an IC50 of 4.5-27 nmoL/mg mitochondrial protein. Tetradifon exerts oligomycin-like activity by inhibiting the oxidative phosphorylation process, inducing oxidative stress and interfering with bone metabolism. Tetradifon is currently mainly used in the research of mitochondrial function regulation, bone remodeling mechanism and nephrotoxicity of environmental pollutants .
loading...
    loading...
Cat. No.: HY-Y1840
CAS No.: 150-19-6
3-Methoxyphenol is an environmental pollutant. 3-Methoxyphenol occurs in the aroma components of dried bonito. 3-Methoxyphenol potentially enhances GABA-evoked responses of α1β1 GABAA receptors by increasing the affinity of GABA binding sites. 3-Methoxyphenol is used as a flavoring substance in food and animal feed. 3-Methoxyphenol prolongs pentobarbital-induced sleeping time and reduces elevated plus maze behavior .
loading...
    loading...
Cat. No.: HY-W009154
CAS No.: 6825-20-3
3,6-Dibromocarbazole is a glucocorticoid receptor (GR) inhibitor and Environmental pollutant. 3,6-Dibromocarbazole induces abnormal development of zebrafish embryos and disrupts the neurohormonal function of the hypothalamic-pituitary-adrenal axis in zebrafish larvae. 3,6-Dibromocarbazole increases the α-diversity of soil bacteria, alters community structure, enhances interspecific competition, regulates metabolic functions, and changes the abundance of genes related to nitrogen fixation, nitrification and carbon cycling. 3,6-Dibromocarbazole exerts endocrine-disrupting potential by interfering with the gluconeogenesis pathway .
loading...
    loading...
Cat. No.: HY-W041308
CAS No.: 64359-81-5
Synonyms: Kathon 930
Research Areas:  

Endocrinology

DCOIT (Kathon 930) is an isothiazolinone biocide and environmental pollutant that directly binds to G protein α subunits, with KD values of 0.92 mM and 0.4 mM for Gαs and Gαi, respectively. Binding of DCOIT to Gαi enhances the interaction between Gαi and mitochondrial calcium uniporter (MCU), alters the subcellular distribution of intracellular Ca 2+, and activates PKC/MEK/ERK signaling. DCOIT upregulates CYP19a transcription and aromatase activity, thereby disrupting steroid hormone homeostasis. DCOIT is used in studies of reproductive endocrine disruption and environmental toxicology .
loading...
    loading...
Cat. No.: HY-W792491
CAS No.: 423-41-6
Research Areas:  

Others

Perfluoropropanesulfonic acid is an ultrashort-chain per- and polyfluoroalkyl substance (PFAS). Perfluoropropanesulfonic acid is an environmental pollutant .
loading...
    loading...
Cat. No.: HY-W001953
CAS No.: 1592-38-7
2-Naphthalenemethanol is the metabolite of environmental pollutant 2-methylnaphthalene. 2-Naphthalenemethanol covalently binds to alveolar protein and induces pulmonary toxicity .
loading...
    loading...
Cat. No.: HY-W096997A
CAS No.: 142-31-4
Synonyms: Sodium capryl sulfate, 95%
Sodium octyl sulfate (Sodium capryl sulfate; SOS), 95% is a medium-chain anionic surfactant. Sodium octyl sulfate (SOS), 95% exhibits strong hydrophobic interactions with serum albumins (such as human serum albumin HSA and bovine serum albumin BSA), but only weak interactions with other proteins including myoglobin and hemoglobin. Sodium octyl sulfate (SOS), 95% acts as an environmental pollutant in freshwater ecosystems, mimicking the interspecific pheromones released by *Daphnia magna* to induce the formation of multicellular colonies in green algae .
loading...
    loading...
Cat. No.: HY-W004769
CAS No.: 230-27-3
Synonyms: α-Naphthoquinoline
Research Areas:  

Others

Benzo[h]quinolone is a widespread environmental pollutant. Benzo[h]quinolone is mutagenic. Benzo(h)quinoline derivatives can serve as G-quadruplex binding agents .
loading...
    loading...
Cat. No.: HY-W587805
CAS No.: 41997-13-1
Synonyms: FHxSA
Research Areas:  

Others

Perfluorohexane sulfonamide (FHxSA) is the inhibitor for carbonic anhydrase, that inhibits bovine CA and human CA II with IC50 of 0.122 and 1.38 μM. Perfluorohexane sulfonamide is a delayed-action insecticide, that can be used to control red fire ants (Solenopsis invicta). Perfluorohexane sulfonamide could be a environmental pollutant .
loading...
    loading...
Cat. No.: HY-E70418
CAS No.: 9048-63-9
Epoxide hydrolase is an enzyme responsible for catalyzing the reaction between epoxides and water, converting epoxide groups into diols. Epoxide hydrolase plays a key role in the metabolism of environmental pollutants and lipids, contributing to detoxification, inflammation responses, and the regulation of cardiovascular system health. Additionally, epoxide hydrolase can be used in asymmetric catalytic reactions, such as the asymmetric ring-opening of epoxides, to produce chiral drug molecules .
loading...
    loading...
Cat. No.: HY-W090065
CAS No.: 93324-65-3
Synonyms: 1-Pyrenemethylamine hydrochloride
Pyren-1-ylmethanamine hydrochloride, Pyren-1-ylmethanamine hydrochloride is commonly used as a fluorescent probe in biochemistry and molecular biology to detect and study nucleic acids, proteins and other biomolecules, moreover, it has been used in analytical chemistry Among them, for the detection of heavy metals and other pollutants in environmental samples, the pyrene group in the molecule exhibits strong fluorescence properties, which makes it useful as a sensitive and selective detector in various applications.
loading...
    loading...
Cat. No.: HY-W004460
CAS No.: 781-43-1
9,10-Dimethylanthracene is a polycyclic aromatic hydrocarbon that acts as a DNA-damaging agent. 9,10-Dimethylanthracene is promising for research of carcinogenic risks of environmental pollutants .
loading...
    loading...
Cat. No.: HY-W012278
CAS No.: 56-55-3
Synonyms: Tetraphene
Benz[a]anthracene (Tetraphene) is a polycyclic aromatic hydrocarbon pollutant and also a ligand of aryl hydrocarbon receptor 2 (AHR2), with a pIC50 of 7.319. Benz[a]anthracene can be detected in spruce needles near aluminum smelters. Exposure to Benz[a]anthracene during zebrafish embryonic stage activates the AHR-CYP1A signaling pathway and induces AHR2 expression, leading to social behavioral deficits that persist into adulthood, accompanied by impaired neuro-immune interaction, while anxiety levels remain unaffected. Benz[a]anthracene can be used in studies related to PAH environmental toxicology, developmental neurotoxicity and biodegradation .
loading...
    loading...
Cat. No.: HY-W271064
CAS No.: 2381-21-7
1-Methylpyrene is a ubiquitous environmental pollutant and rodent carcinogen. Its mutagenic activity depends on sequential activation by various CYP and sulfotransferase (SULT) enzymes. 1-Methylpyrene induces chromosome loss and mitotic disturbance, proba
loading...
    loading...