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125 Results for "

Estrogen Receptor Modulator

" in MedChemExpress (MCE) Product Catalog:

Products (125)

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282

Tamoxifen Citrate

282 Publications Verification

Cat. No.: HY-13757

CAS No.: 54965-24-1

Purity: 99.93%

Synonyms: ICI 46474; (Z)-Tamoxifen Citrate; trans-Tamoxifen Citrate

Target:

Estrogen Receptor/ERR HSP Autophagy Apoptosis

Research Areas:

Infection Neurological Disease Inflammation/Immunology Cancer

Tamoxifen Citrate (ICI 46474) is an orally active, selective estrogen receptor modulator (SERM) which blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells.Tamoxifen Citrate is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen Citrate also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC₅₀ of 0.1 μM and 1.8 μM, respectively. Tamoxifen Citrate activates autophagy and induces apoptosis. Tamoxifen Citrate can also be used to induce gene knockout in CreER transgenic mice .

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282

Tamoxifen

282 Publications Verification

Cat. No.: HY-13757A

CAS No.: 10540-29-1

Purity: 99.78%

Synonyms: ICI 47699; (Z)-Tamoxifen; trans-Tamoxifen

Target:

Estrogen Receptor/ERR HSP Autophagy Apoptosis

Research Areas:

Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer

Tamoxifen (ICI 47699) is an orally active, selective estrogen receptor modulator (SERM) which blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells. Tamoxifen is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC₅₀ of 0.1 μM and 1.8 μM, respectively. Tamoxifen activates autophagy and induces apoptosis. Tamoxifen can also be dissolved in corn oil (HY-Y1888) for use in inducing gene knockout in CreER transgenic mice. Tamoxifen has better solubility in corn oil compared to Tamoxifen Citrate (HY-13757) .

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4-Hydroxytamoxifen

62 Cited Publications

Cat. No.: HY-16950

CAS No.: 68047-06-3

Synonyms: (Z)-4-Hydroxytamoxifen; trans-4-Hydroxytamoxifen; (Z)-Afimoxifene

Target:

Estrogen Receptor/ERR

Research Areas:

Cancer

4-Hydroxytamoxifen ((Z)-4-Hydroxytamoxifen) is an orally active, selective estrogen receptor modulator (SERM). 4-Hydroxytamoxifen ((Z)-4-Hydroxytamoxifen) is also the active metabolic form of Tamoxifen (HY-13757A) in vivo and can be used to induce gene knockout in transgenic mice expressing CreER .

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