4 Results for "

Etomidate acid

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "Etomidate acid" in MCE Product Catalog:

Cat. No.: HY-116666
CAS No.: 56649-48-0
Target:  

Drug Derivative

Research Areas:  

Metabolic Disease

Etomidate acid is an Etomidate analog. Etomidate acid inhibits the binding of metyrapone (Metyrapol) and 4-iodometomidate to rat adrenal membrane sites .
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Cat. No.: HY-116666S
(Rac)-Etomidate acid-d5 is the deuterium labeled (Rac)-Etomidate acid .
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Cat. No.: HY-169432
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

TET-13 is a positive allosteric modulator of GABAA receptor with an EC50 of 5.65 μM, lower than that of Etomidate (EC50: 9.29 μM). TET-13 shows potent anesthetic effects in both mice and rats (ED50: 0.48 mg/kg and 0.69 mg/kg, respectively) .
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Cat. No.: HY-121102
CAS No.: 1257067-10-9
Carboetomidate is a pyrrole derivative analogous to the sedative-hypnotic drug Etomidate, which induces general anesthesia while avoiding the inhibition of adrenal steroid synthesis. Carboetomidate enhances GABAA receptor function via β2/β3 subunits, inhibits neuronal nicotinic acetylcholine receptors (nAChR) and 5-HT3A receptors, and increases plasma IL-10 levels during endotoxemia. Carboetomidate is applicable to research related to sepsis and sleep disorders .
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