3 Results for "

FAP-positive cells

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "FAP-positive cells" in MCE Product Catalog:

Cat. No.: HY-W668749
CAS No.: 2374782-82-6
Target:  

FAP

Research Areas:  

Inflammation/Immunology

3BP-3580 (compound 11) is a conjugate targeting FAP that binds to FAP-positive cells via the FAPI moiety and internalizes, delivering the payload to FAP-expressing cells, thereby inhibiting RA FLS proliferation, migration, and invasion, reducing inflammatory cytokine expression, and suppressing pannus formation. 3BP-3580 can be used for research on rheumatoid arthritis .
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Cat. No.: HY-W668749A
Target:  

FAP

Research Areas:  

Inflammation/Immunology

3BP-3580 TFA (compound 11) is a conjugate targeting FAP that binds to FAP-positive cells via the FAPI moiety and internalizes, delivering the payload to FAP-expressing cells, thereby inhibiting RA FLS proliferation, migration, and invasion, reducing inflammatory cytokine expression, and suppressing pannus formation. 3BP-3580 TFA can be used for research on rheumatoid arthritis .
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Cat. No.: HY-P991995
Synonyms: OMTX705 antibody

Target:  

ADC Antibodies FAP

Research Areas:  

Cancer

OMTX005 (OMTX705 antibody) is a humanized anti-FAP IgG1 monoclonal antibody that specifically binds to human (EC50: 0.33 nM)/mouse (EC50: 0.14 nM) FAP proteins and FAP-positive cells. OMTX005 exhibits no cytotoxicity when used alone and fails to induce an increase in caspase 3/7 activity in relevant cells. OMTX005 can be used to synthesize the ADC molecule OMTX705 for tumor research .
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