5 Results for "

FCR3

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "FCR3" in MCE Product Catalog:

1
Borrelidin
Borrelidin
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1 Cited Publications
Cat. No.: HY-N6742
CAS No.: 7184-60-3
Synonyms: Treponemycin
Category:  

Infection Microorganisms Macrolide Antibiotics Antibiotics Anti-parasitic Disease Research Antibacterial Disease Research Fields

Target:  

CDK Parasite Apoptosis Antibiotic

Borrelidin (Treponemycin) is a bacterial and eukaryal threonyl-tRNA synthetase inhibitor which is a nitrile-containing macrolide antibiotic isolated from Streptomyces rochei . Borrelidin is an inhibitor of Cdc28/Cln2 of the budding yeast, with an IC50 of 24 μM . Borrelidin is a potent angiogenesis inhibitor, with an IC50 of 0.8 nM. Borrelidin induces apoptosis in the tube-forming cells [3]. Borrelidin has strong antimalarial activities, with IC50s of 1.9 nM and 1.8 nM against K1 and FCR3 strains of Plasmodium falciparum, respectively .
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(2S)-2'-Methoxykurarinone
(2S)-2'-Methoxykurarinone
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Cat. No.: HY-N1746
CAS No.: 270249-38-2
Synonyms: 2'-O-Methylkurarinone
Category:  

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