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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
FF2039
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "FF2039" in MCE Product Catalog:
Cat. No.: HY-172159
Research Areas:
FF2039 is a pan-HDAC PROTAC degrader that binds to DCAF11, acting on HDAC6, HDAC1, HDAC2 and HDAC4. FF2039 recruits the DCAF11 E3 ligase and mediates the polyubiquitination and degradation of HDACs via the ubiquitin-proteasome system. FF2039 induces cell cycle arrest, apoptosis, cytotoxicity and antiproliferative activity in cancer cells, and reduces the clonogenic capacity of cancer cells. FF2039 is applicable to research related to multiple myeloma, triple-negative breast cancer and glioblastoma .
Cat. No.: HY-W957284
CAS No.: 2940939-13-7
Target:
Research Areas:
DCAF11 ligand 1 is the ligand for E3 ligase DCAF11 and can be used for PROTAC synthesis of FF2039 (HY-172159) .
Cat. No.: HY-W881439
CAS No.: 2703752-86-5
Target:
Research Areas:
1-(1,1-Dimethylethyl) tridecanedioate is a PROTAC Linker and can be used for PROTAC synthesis, such as
FF2039 (HY-172159) .
Cat. No.: HY-172185
Research Areas:
E3 Ligase Ligand-linker Conjugate 172 is the conjugate composed of an E3 ligase ligand and a linker, and can be used for synthesis of PROTAC degrader FF2039 (HY-172159) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
