3 Results for "

FIV

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "FIV" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-124757
CAS No.: 932359-76-7
Purity:  99.87%
Target:  

Proteasome Mitosis

Research Areas:  

Cancer

FiVe1 is a vimentin (VIM) inhibitor. FiVe1 binds to the rod domain of VIM, causing metaphase VIM disassembly and hyperphosphorylation at Ser56, ultimately leading to mitotic catastrophe, multinucleation, and loss of stemness. FiVe1 has anticancer activity against soft tissue sarcomas. FiVe1 increases the sensitivity of ovarian cancer to Cisplatin (HY-17394). FiVe1 can be used for researches of mesenchymal cancers (including breast cancer and soft tissue sarcoma) and ovarian cancers .
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Cat. No.: HY-P71572
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SH3PXD2A; FIVe SH3 Domain-Containing Protein; Prev. SH3MD1; Adapter Protein TKS5; FISH; TKS5; KIAA0418; SH3 Multiple Domains Protein 1; Tyrosine Kinase Substrate With FIVe SH3 Domains; Adaptor Protein TKS5; SH3 And PX Domain-Containing Protein 2A; FIVe SH
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P83257
Synonyms: CC2D1A; AKI1; LGD2; Coiled-coil and C2 domain-containing protein 1A; Akt kinase-interacting protein 1; FIVe prime repressor element under dual repression-binding protein 1; Putative NF-kappa-B-activating protein 023N

Host:  

Rabbit

Application:  

WB, ICC/IF, FC

Reactivity:  

Human, Mouse, Rat

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