1 Result for "

FM 213

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "FM 213" in MCE Product Catalog:

Cat. No.: HY-P11891
Target:  

PD-1/PD-L1

Research Areas:  

Cancer

FM213 is a PD-L1 inhibitor with a human IC50 of 323 nM. FM213 blocks PD-1/PD-L1 protein-protein interactions, and promotes endocytosis and lysosome-dependent degradation of PD-L1 on the surface of cancer cells. FM213 binds to PD-L1 on cancer cells and exosomes, and enhances the recognition and killing of cancer cells by human PBMC. Combination of FM213 with the TIGIT inhibitor DTBP-3 (HY-P11903) enhances anti-tumor immunity. FM213 can be used in research related to non-small cell lung cancer .
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