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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
FSGS
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "FSGS" in MCE Product Catalog:
2
2 Cited Publications
Target:
Research Areas:
FSG67 is a glycerol 3-phosphate acyltransferase (GPAT) inhibitor with an IC50 of 24 μM .
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1 Cited Publications
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AC1903 is a specific and selective inhibitor of TRPC5 and has podocyte-protective properties. AC1903 does no effects on TRPC4 or TRPC6 currents and shows no off-target effects in kinase profiling assays. AC1903 suppresses severe proteinuria and prevents podocyte loss in focal segmental glomerulosclerosis (FSGS) rat model .
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Nifurpirinol (P-7138) is a selective prosubstrate of bacterial nitroreductase (NTR). NTR catalyzes the reduction of nifurpirinol to generate cytotoxic metabolites that induce apoptosis in target cells. Nifurpirinol selectively ablates NTR-expressing cells such as pancreatic β cells, osteoblasts, dopaminergic neurons, and podocytes in transgenic zebrafish models. Nifurpirinol can be used in regeneration studies and disease modeling such as focal segmental glomerulosclerosis (FSGS) .
Category:
Target:
Cat. No.: HY-W744699
CAS No.: 1438-66-0
Synonyms: (+)-Larixol
Cat. No.: HY-RS00226
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Research Areas:
ACTN4 Human Pre-designed siRNA Set A contains three designed siRNAs for ACTN4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P991666
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Research Areas:
Cat. No.: HY-135470R
CAS No.: 13411-16-0
Synonyms: P-7138 (Standard)
Target:
Research Areas:
Nifurpirinol (P-7138) (Standard) is the analytical standard of Nifurpirinol (HY-135470). This product is intended for research and analytical applications. Nifurpirinol (P-7138) is a selective prosubstrate of bacterial nitroreductase (NTR). NTR catalyzes the reduction of nifurpirinol to generate cytotoxic metabolites that induce apoptosis in target cells. Nifurpirinol selectively ablates NTR-expressing cells such as pancreatic β cells, osteoblasts, dopaminergic neurons, and podocytes in transgenic zebrafish models. Nifurpirinol can be used in regeneration studies and disease modeling such as focal segmental glomerulosclerosis (FSGS) .
Cat. No.: HY-W745090
CAS No.: 58024-13-8
Cat. No.: HY-P701113
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ACTN4; Actinin Alpha 4 Isoform 3; Prev. FSGS1; Actinin Alpha 4 Isoform 2; Focal Segmental Glomerulosclerosis 1; Actinin Alpha 4 Isoform 1; Non-Muscle Alpha-Actinin 4; ACTN4 Protein; Alpha-Actinin-4; ACTININ-4; Actinin, Alpha 4, Isoform CRA_a; FSGS; Actini
Species:
Human
Source:
HEK293
Cat. No.: HY-P703229
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: TRPC6; TRP6; Short transient receptor potential channel 6; TrpC6; Transient receptor protein 6; TRP-6; TrpC6; Transient Receptor Potential Cation Channel, Subfamily C, Member 6; FSGS2; Transient Receptor Potential Cation Channel Subfamily C Member 6; Foca
Species:
Human
Source:
HEK293
Cat. No.: HY-P75504
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: APOL1; Apolipoprotein L 1; Prev. APOL; APOL1 Protein; Apolipoprotein L1-B3; APOL-I; Apolipoprotein L; ApoL-I; CDNA FLJ59906, Moderately Similar To Apolipoprotein-L1; FSGS4; Apolipoprotein L 1 Isoform 2; APO-L; Apolipoprotein L 1 Isoform 1; Apo-L; Alternat
Species:
Human
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
