15 Results for "

Fas/FasL

" in MedChemExpress (MCE) Product Catalog:
Products (15)

15 Results for "Fas/FasL" in MCE Product Catalog:

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3
3 Cited Publications
Cat. No.: HY-P10102
CAS No.: 629628-53-1
Research Areas:  

Inflammation/Immunology Cancer

Kp7-6 is a Fas mimetic peptide and also a Fas/FasL antagonist. Kp7-6 specifically binds to Fas and FasL, disrupts receptor complexes, and blocks downstream apoptosis signaling pathways. Kp7-6 inhibits the phosphorylation of ERK1-2, induces the phosphorylation of IκBα, and activates NF-κB. Kp7-6 inhibits the activation of caspase-8, caspase-3 and JNK, and suppresses human amylin-induced β-cell apoptosis. Kp7-6 inhibits FasL-induced lymphoid cytotoxicity and apoptosis. Kp7-6 reduces local tumor FasL expression, increases CD8 +Fas + T cell infiltration, and decreases tumor volume in pancreatic neuroendocrine tumor models. Kp7-6 prevents concanavalin A-induced liver injury in mice. Kp7-6 is applicable to research related to type 2 diabetes, concanavalin A-induced hepatitis and pancreatic neuroendocrine tumors .
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1
1 Cited Publications
Cat. No.: HY-150190
CAS No.: 2304465-89-0
Purity:  99.38%
Research Areas:  

Cancer

F5446 (Compound 1) is a selective small molecule inhibitor of SUV39H1 methyltransferase. F5446 decreases H3K9me3 deposition at the FAS promoter, increases Fas expression and increases colorectal carcinoma cell sensitivity to FasL-induced apoptosis in vitro. F5446 suppresses human colon tumor xenograft growth in vivo .
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1
1 Cited Publications
Cat. No.: HY-133897
CAS No.: 26988-72-7
Purity:  99.18%
Synonyms: 1-Methyl-DL-tryptophan; (Rac)-NLG-8189
(Rac)-Indoximod (1-Methyl-DL-tryptophan) is an indoleamine 2,3-dioxygenase (IDO) inhibitor. Co-treatment with IFN-γ and (Rac)-Indoximod markedly reduces the activity of human cardiac myofibroblasts (hCMs) expressing α-SMA and induces apoptosis through up-regulating the IRF-1, Fas, and FasL genes .
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1
1 Cited Publications
Cat. No.: HY-P700052AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FasLG; TNLG1A; Prev. APT1LG1; CD95L; Prev. TNFSF6; APTL; FasL; Tumor Necrosis Factor (Ligand) Superfamily, Member 6; Tumor Necrosis Factor Ligand Superfamily Member 6; Mutant Tumor Necrosis Factor Family Member 6; Fas Antigen Ligand; Apoptosis (APO-1) Ant
Species:  
Human
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-P700176AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FasLG; TNLG1A; Prev. APT1LG1; CD95L; Prev. TNFSF6; APTL; FasL; Tumor Necrosis Factor (Ligand) Superfamily, Member 6; Tumor Necrosis Factor Ligand Superfamily Member 6; Mutant Tumor Necrosis Factor Family Member 6; Fas Antigen Ligand; Apoptosis (APO-1) Ant
Species:  
Mouse
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-P700520
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FasLG; TNLG1A; Prev. APT1LG1; CD95L; Prev. TNFSF6; APTL; FasL; Tumor Necrosis Factor (Ligand) Superfamily, Member 6; Tumor Necrosis Factor Ligand Superfamily Member 6; Mutant Tumor Necrosis Factor Family Member 6; Fas Antigen Ligand; Apoptosis (APO-1) Ant
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-N12378
CAS No.: 514-51-2
β-Patchoulene is an orally active anti-inflammatory, antioxidant, and anti-apoptotic agent. β-Patchoulene inhibits the NF-κB, TLR4, and cAMP/PKA/CREB signaling pathways; activates the Sirt1/Nrf2 and AMPK signaling pathways; and targets Fas/FasL, Caspase-3, ERK1/2, ROCK1/MLC2 for inhibition. β-Patchoulene regulates cytokine secretion, inflammatory cell infiltration, lipid peroxidation, cell polarization, gut microbiota, and lipid metabolism, restores barrier function, mitochondrial function, and cell viability, and exhibits repellent activity against Spodoptera exigua larvae. β-Patchoulene can be used in research related to various inflammatory, ischemic, fibrosis-associated diseases, as well as hepatocellular carcinoma .
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Cat. No.: HY-P10815
Research Areas:  

Others

IP3RCYT is an IP3R inhibitory peptide, which can inhibit the binding of cytochrome C to IP3R with an IC50 about 100 nM. IP3RCYT regulates calcium signaling within cells. P3RCYT inhibits apoptosis in HeLa and Jurkat cells treated with Staurosporine (HY-15141) or Membrane-bound Fas ligand (FasL) .
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Cat. No.: HY-P99133

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology Cancer

Anti-Mouse Fas Ligand Antibody (MFL3) is an anti-mouse Fas Ligand IgG antibody inhibitor derived from host Armenian Hamster. Anti-Mouse Fas Ligand Antibody (MFL3) can block Fas Ligand (FasL). Anti-Mouse Fas Ligand Antibody (MFL3) can be used for the researches of cancer and immunology .
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Cat. No.: HY-P84345
Synonyms: CD178; APT1LG1; CD95L; FasL; TNFSF6; FasLG; Tumor necrosis factor ligand superfamily member 6; Apoptosis antigen ligand; CD95 ligand; Fas antigen ligand; APTL; CD95-L; Fas ligand; FasL

Host:  

Mouse

Application:  

ICC/IF, FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P84345A
Synonyms: CD178; APT1LG1; CD95L; FasL; TNFSF6; FasLG; Tumor necrosis factor ligand superfamily member 6; Apoptosis antigen ligand; CD95 ligand; Fas antigen ligand; APTL; CD95-L; Fas ligand; FasL

Host:  

Mouse

Application:  

ICC/IF, FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P72658A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FasLG; TNLG1A; Prev. APT1LG1; CD95L; Prev. TNFSF6; APTL; FasL; Tumor Necrosis Factor (Ligand) Superfamily, Member 6; Tumor Necrosis Factor Ligand Superfamily Member 6; Mutant Tumor Necrosis Factor Family Member 6; Fas Antigen Ligand; Apoptosis (APO-1) Antigen Ligand 1; CD95 Ligand; Tumor Necrosis Factor Ligand 1A; CD178; CD178 Antigen; Fas Ligand (TNF Superfamily, Member 6); ALPS1B; Apoptosis Antigen Ligand; FasL; Fas Ligand; CD95-L
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P74157
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FasLG; TNLG1A; Prev. APT1LG1; CD95L; Prev. TNFSF6; APTL; FasL; Tumor Necrosis Factor (Ligand) Superfamily, Member 6; Tumor Necrosis Factor Ligand Superfamily Member 6; Mutant Tumor Necrosis Factor Family Member 6; Fas Antigen Ligand; Apoptosis (APO-1) Ant
Species:  
Mouse
Source:  
P. pastoris
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Cat. No.: HY-P700521
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FasLG; TNLG1A; Prev. APT1LG1; CD95L; Prev. TNFSF6; APTL; FasL; Tumor Necrosis Factor (Ligand) Superfamily, Member 6; Tumor Necrosis Factor Ligand Superfamily Member 6; Mutant Tumor Necrosis Factor Family Member 6; Fas Antigen Ligand; Apoptosis (APO-1) Ant
Species:  
Human
Source:  
P. pastoris
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Cat. No.: HY-P74158
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FasLG; TNLG1A; Prev. APT1LG1; CD95L; Prev. TNFSF6; APTL; FasL; Tumor Necrosis Factor (Ligand) Superfamily, Member 6; Tumor Necrosis Factor Ligand Superfamily Member 6; Mutant Tumor Necrosis Factor Family Member 6; Fas Antigen Ligand; Apoptosis (APO-1) Ant
Species:  
Human
Source:  
P. pastoris
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