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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
270 Results for "
Fc-containing scaffold
" in MedChemExpress (MCE) Product Catalog:
Products (270)
270 Results for "Fc-containing scaffold" in MCE Product Catalog:
72
72 Publications Verification
Synonyms: endo-IWR 1; IWR-1-endo
Research Areas:
IWR-1 (IWR-1-endo) is a tankyrase inhibitor targeting Wnt/β-catenin (IC50 = 180 nM). IWR-1 compromises critical steps of the canonical Wnt signaling, namely translocation of β-catenin to the nucleus and subsequent TCF/LEF activation and expression of Wnt/β-catenin downstream targets. IWR-1 promotes β-catenin phosphorylation by promoting stability of Axin-scaffolded destruction complexes. IWR-1 can be studied in research for anti-tumor purposes, and diseases such as osteosarcoma, colorectal cancer and psoriasis .
15
Research Areas:
Fluorescein (Uranine) sodium is widely used as a fluorescent tracer in medicinal and biological applications and tumor infected tissues tracer. Fluorescein (Uranine) sodium is a representative green fluorophore that has been widely used as a scaffold of practically useful green fluorescent probes .
15
7
7 Cited Publications
Synonyms: Tegavivint; BC2059
Tegatrabetan (BC2059) is a β-Catenin antagonist. Tegatrabetan disrupts the binding of β-catenin with the scaffold protein transducin β-like 1 (TBL1) .
7
7 Cited Publications
Cat. No.: HY-44076
CAS No.: 85073-19-4
Synonyms: Lithium phenyl-2,4,6-trimethylbenzoylphosphinate
6
4
3
3 Cited Publications
Synonyms: TAS6417; CLN-081
Zipalertinib (TAS6417; CLN-081) is a highly effective, orally active and pan-mutation-selective EGFR tyrosine kinase inhibitor with a unique scaffold fitting into the ATP-binding site of the EGFR hinge region, with IC50 values ranging from 1.1-8.0 nM .
1
Target:
Research Areas:
2,2'-Bipyridine is the unique molecular scaffold of the bioactive natural products. 2,2'-Bipyridine is extensively used as the core structure of many chelating ligands by acting as a bridge in the arrangement of the catalytic center. 2,2'-Bipyridine shows robust redox stability and hyperglycemic activity .
1
1 Cited Publications
Cat. No.: HY-W110584
CAS No.: 24249-95-4
1
Benzoyleneurea possesses anti-bacterial activity. Benzoyleneurea scaffold can be used in the synthesis of novel protein geranylgeranyltransferase-I (PGGTase-I) inhibitors .
1
Category:
Infection Natural Products Plant Matricaria recutita L. Extract Compositae/Asteraceae Extract Disease Research Fields
Target:
1
1 Cited Publications
Cat. No.: HY-P72066
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ISCU; Iron-Sulfur Cluster Assembly Enzyme ISCU, Mitochondrial; Prev. NIFUN; Iron-Sulfur Cluster scaffold Homolog (E. Coli); NifU-Like N-Terminal Domain-containing Protein; IscU Iron-Sulfur Cluster scaffold Homolog; Iron-Sulfur Cluster Assembly Enzyme ISCU
Species:
Human
Source:
Sf9 insect cells
1
1 Cited Publications
Cat. No.: HY-W250312
CAS No.: 24980-41-4
Research Areas:
Polycaprolactone is a biodegradable polyester commonly used in various biomedical and industrial applications. It is a white waxy polymer that can be molded into various shapes and forms. Polycaprolactone has various properties suitable for these applications, including low melting point, high flexibility and slow biodegradation rate. It can be used as a raw material for the production of tissue engineering scaffolds, drug delivery systems, and medical implants. In addition, it is used as a binder in the production of adhesives, coatings and paints.
1
1 Cited Publications
Cat. No.: HY-W089353
CAS No.: 194235-40-0
1
1 Cited Publications
Synonyms: Carboxymethyl cellulose CM-32; CM-32
Cat. No.: HY-W110542G
CAS No.: 26570-48-9
Synonyms: PEGDA (MW 6000)
Cat. No.: HY-W110542J
CAS No.: 26570-48-9
Synonyms: PEGDA (MW 700)
Cat. No.: HY-P10956
CAS No.: 2891912-36-8
Synonyms: LY3541105
Target:
Research Areas:
Cat. No.: HY-W110542D
CAS No.: 26570-48-9
Synonyms: PEGDA (MW 1000)
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
