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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
FimH
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "FimH" in MCE Product Catalog:
4
4 Cited Publications
Synonyms: Antibiotic-202
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Research Areas:
Sibofimloc (Antibiotic-202) is a first-in-class, gut-restricted, orally active FimH adhesion inhibitor extracted from patent WO2014100158A1, Compound Example 202. Sibofimloc has anti-bacterial infective activity. Sibofimloc is developed for inflammatory bowel disease (IBD) .
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M4284 is a selective and orally active biphenyl mannoside FimH antagonist. M4284 has activities against different UPEC (Urinary tract infections (UTI) caused by uropathogenic E. coli) strains in different host genetic backgrounds and gut microbial community contexts .
Cat. No.: HY-12820R
CAS No.: 1616113-45-1
Synonyms: Antibiotic-202 (Standard)
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Research Areas:
Sibofimloc (Standard) is the analytical standard of Sibofimloc. This product is intended for research and analytical applications. Sibofimloc (Antibiotic-202) is a first-in-class, gut-restricted, orally active FimH adhesion inhibitor extracted from patent WO2014100158A1, Compound Example 202. Sibofimloc has anti-bacterial infective activity. Sibofimloc is developed for inflammatory bowel disease (IBD)[1][2].
Cat. No.: HY-187797
CAS No.: 2408524-70-7
Synonyms: GSK3882347
Luxafimloc (GSK3882347) is a FimH inhibitor and anti-infective agent. Luxafimloc inhibits the activity of the FimH adhesin molecule. Luxafimloc reduces the bacterial load in the bladder of mice with acute cystitis induced by Klebsiella pneumoniae infection. Luxafimloc can be used in studies related to urinary tract infections, including cystitis, uncomplicated urinary tract infection, complicated urinary tract infection, catheter-associated urinary tract infection, acute urinary tract infection, recurrent urinary tract infection, and chronic urinary tract infection .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
