12 Results for "

Flavonolignan

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "Flavonolignan" in MCE Product Catalog:

10
Silybin
Silybin
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10 Publications Verification
Cat. No.: HY-N0779A
CAS No.: 802918-57-6
Synonyms: Silibinin
Category:  

Silybum marianum (Linn.) Gaertn Extract Flavanonols Plant Flavonoids Phenols Polyphenols Compositae/Asteraceae Extract Disease Research Fields Inflammation/Immunology

Target:  

Apoptosis

Silybin is a flavonolignan isolated from milk thistle (Silybum marianum) seeds. Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity .
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4
Silychristin
Silychristin
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4 Cited Publications
Cat. No.: HY-N0647
CAS No.: 33889-69-9
Category:  

Silybum marianum (Linn.) Gaertn Extract Flavanonols Plant Flavonoids Phenols Polyphenols Compositae/Asteraceae Extract Disease Research Fields Endocrinology

Target:  

Monocarboxylate Transporter

Silychristin is an abundant flavonolignan present in the fruits of Silybum marianum, with antioxidant properties. Silychristin is a potent inhibitor of the thyroid hormone transporter MCT8, and elicits a strong inhibition of T3 uptake with an IC50 of 110 nM .
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2
Isosilybin B
Isosilybin B
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2 Cited Publications
Cat. No.: HY-N7045
CAS No.: 142796-22-3
Category:  

Silybum marianum (Linn.) Gaertn Extract Flavanonols Plant Flavonoids Phenols Polyphenols Compositae/Asteraceae Extract Disease Research Fields Cancer

Target:  

Androgen Receptor Apoptosis CDK Caspase PSMA

Isosilybin B is a flavonolignan. Isosilybin B can be isolated from Silybum marianum. Isosilybin B can regulate cell cycle-related proteins (e.g., reduce cyclins (D3, D1, A, E), Cdk4, Cdk2, Cdc25A), and activate Caspases (Caspase-9 and Caspase-3). Isosilybin B can promote Apoptosis, reduce androgen receptor (AR) and PSA. Isosilybin B has anticancer activity against prostate cancer .
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1
Silydianin
Silydianin
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1 Cited Publications
Cat. No.: HY-N0646
CAS No.: 29782-68-1
Category:  

Plant Flavonoids Flavonones Phenols Polyphenols Other Families Extract Disease Research Fields Cancer

Target:  

Phosphatase Endogenous Metabolite Tyrosinase Apoptosis Interleukin Related

Silydianin is a flavonolignan. Silydianin can be obtained from Silybum marianum. Silydianin inhibits PTP1B with an IC50 of 17.38 μM. Silydianin inhibits both monophenolase and diphenolase of tyrosinase significantly, with IC50s of 2.6 μM and 16.5 μM, respectively. Silydianin induces Apoptosis and reduces cytokines (IL-4 and IL-5). Silymarin has antioxidant, cytoprotective and immunomodulatory effects. Silydianin has antitumor activity against prostate cancer. Silymarin can be used in allergic asthma research .
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2,3-Dehydrosilybin B
2,3-Dehydrosilybin B
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Cat. No.: HY-N12360A
CAS No.: 142796-24-5
Category:  

Silybum marianum (Linn.) Gaertn Extract Flavonols Plant Flavonoids Compositae/Asteraceae Extract

Target:  

UGT

2,3-Dehydrosilybin B is an enantiomer formed by the oxidation of the natural flavonolignans silybin A .
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(±)-Hydnocarpin
(±)-Hydnocarpin
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Cat. No.: HY-N10986
CAS No.: 298704-61-7
Category:  

Flavonoids Microorganism Other Flavonoids

Target:  

Bacterial

(±)-Hydnocarpin is a flavonolignan. (±)-Hydnocarpin can inhibit the growth of S. aureus with a MIC50 value of 3.1 μM .
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Silybin (Standard)
Silybin (Standard)
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Cat. No.: HY-N0779AR
CAS No.: 802918-57-6
Synonyms: Silibinin (Standard)
Category:  

Silybum marianum (Linn.) Gaertn Extract Flavanonols Plant Flavonoids Phenols Polyphenols Compositae/Asteraceae Extract

Target:  

Reference Standards Apoptosis

Silybin (Standard) is the analytical standard of Silybin. This product is intended for research and analytical applications. Silybin is a flavonolignan isolated from milk thistle (Silybum marianum) seeds. Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity .
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Silyamandin
Silyamandin
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Cat. No.: HY-N8180
CAS No.: 1009565-36-9
Category:  

Flavonols Lignans Compositae/Asteraceae Extract Silybum marianum (Linn.) Gaertn Extract Plant Flavonoids Other Diseases Phenols Polyphenols Phenylpropanoids Disease Research Fields

Target:  

Others

Silyamandin is a flavonolignan compound. Silydianin can form Silyamandin through oxidative degradation .
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Lepidiline B
Lepidiline B
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Cat. No.: HY-129584
CAS No.: 596093-97-9
Category:  

Lepidium meyenii Walp. Extract Alkaloids Plant Other Alkaloids Brassicaceae Extract

Target:  

Others

Lepidiline B is a flavonolignan isolated from the roots of Brassicaceae Lepidium meyenii. Lepidiline B exhibits anti-inflammation activities in human cancer cell lines .
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Silychristin (Standard)
Silychristin (Standard)
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Cat. No.: HY-N0647R
CAS No.: 33889-69-9
Category:  

Silybum marianum (Linn.) Gaertn Extract Flavanonols Plant Flavonoids Phenols Polyphenols Compositae/Asteraceae Extract

Target:  

Reference Standards Monocarboxylate Transporter

Silychristin (Standard) is the analytical standard of Silychristin. This product is intended for research and analytical applications. Silychristin is an abundant flavonolignan present in the fruits of Silybum marianum, with antioxidant properties. Silychristin is a potent inhibitor of the thyroid hormone transporter MCT8, and elicits a strong inhibition of T3 uptake with an IC50 of 110 nM .
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Isosilybin B (Standard)
Isosilybin B (Standard)
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Cat. No.: HY-N7045R
CAS No.: 142796-22-3
Category:  

Silybum marianum (Linn.) Gaertn Extract Flavanonols Plant Flavonoids Phenols Polyphenols Compositae/Asteraceae Extract

Target:  

Reference Standards Androgen Receptor Apoptosis CDK Caspase PSMA

Isosilybin B (Standard) is the analytical standard of Isosilybin B (HY-N7045). This product is intended for research and analytical applications. Isosilybin B is a flavonolignan. Isosilybin B can be isolated from Silybum marianum. Isosilybin B can regulate cell cycle-related proteins (e.g., reduce cyclins (D3, D1, A, E), Cdk4, Cdk2, Cdc25A), and activate Caspases (Caspase-9 and Caspase-3). Isosilybin B can promote Apoptosis, reduce androgen receptor (AR) and PSA. Isosilybin B has anticancer activity against prostate cancer .
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Silydianin (Standard)
Silydianin (Standard)
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Cat. No.: HY-N0646R
CAS No.: 29782-68-1
Category:  

Plant Flavonoids Flavonones Phenols Polyphenols Other Families Extract

Target:  

Reference Standards Phosphatase Endogenous Metabolite Tyrosinase Apoptosis Interleukin Related

Silydianin (Standard) is the analytical standard of Silydianin (HY-N0646). This product is intended for research and analytical applications. Silydianin is a flavonolignan. Silydianin can be obtained from Silybum marianum. Silydianin inhibits PTP1B with an IC50 of 17.38 μM. Silydianin inhibits both monophenolase and diphenolase of tyrosinase significantly, with IC50s of 2.6 μM and 16.5 μM, respectively. Silydianin induces Apoptosis and reduces cytokines (IL-4 and IL-5). Silymarin has antioxidant, cytoprotective and immunomodulatory effects. Silydianin has antitumor activity against prostate cancer. Silymarin can be used in allergic asthma research .
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