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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
226 Results for "
Flexible Nano Array tethers
" in MedChemExpress (MCE) Product Catalog:
Products (226)
226 Results for "Flexible Nano Array tethers" in MCE Product Catalog:
9
9 Publications Verification
Cat. No.: HY-114164H
CAS No.: 9002-04-4
Synonyms: EC 3.4.21.5 (Lyophilized); Human Alpha Thrombin (Lyophilized)
Research Areas:
Human α-Thrombin (EC 3.4.21.5; Human Alpha Thrombin) (Lyophilized) is a terminal serine protease in the coagulation cascade, as well as a potent physiological platelet agonist and fibrin-generating enzyme in vivo. Human α-Thrombin catalyzes the conversion of fibrinogen to fibrin for blood clot formation, and activates platelet aggregation by cleaving the protease-activated receptors PAR1 (major) (Kd = 1 nM) and PAR4 (minor) on the platelet surface to expose tethered ligands. Human α-Thrombin also amplifies coagulation via positive feedback by activating coagulation factors V, VIII, XI (FV/FVIII/FXI), and switches to activate protein C to exert anticoagulant effects after binding to thrombomodulin .
This product is in a freeze-dried form.
This product is in a freeze-dried form.
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6 Cited Publications
Xeruborbactam disodium is a potent, ultra-broad-spectrum boronic acid beta-lactamase inhibitor. Xeruborbactam disodium inhibits key serine and metallo beta-lactamases at a nano molar range .
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4 Cited Publications
Synonyms: P-005672 hydrochloride
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Sarecycline hydrochloride is an orally active narrow-spectrum tetracycline derivative antibiotic. Sarecycline hydrochloride has anti-inflammatory activity. Sarecycline hydrochloride inhibits the activity of Gram-positive bacteria and several types of keratobacterium acnes. Sarecycline hydrochloride interferes with tRNA accommodation and tethers mRNA to the 70S ribosome. Sarecycline hydrochloride can be used to study moderate to severe acne
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2 Cited Publications
Cat. No.: HY-D1683
CAS No.: 178119-00-1
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2
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Diethyl phthalate is an orally active plasticizer and detergent base. Diethyl phthalate increases the activities of ACP, ALP, SDH, and ALT in liver, muscle, or both tissues. Diethyl phthalate induces dose-dependent mortality and sluggish behavior in freshwater fish. Diethyl phthalate may induce male reproductive toxicity. Diethyl phthalate is added to plastic polymers to help maintain their flexibility .
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2 Cited Publications
Cat. No.: HY-KD1006
MCE offers a variety of multiplex fluorescence detection kits, featuring high quenching resistance, low cross-contamination, and strong stability. The five-color multiplex fluorescence staining kit can stain four indicators. (MCE offers six VF series dyes: VF 480, VF 520, VF 570, VF 620, VF 690, and VF 780; you can flexibly select according to your actual needs.)
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1 Cited Publications
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AA-T3A-C12 is an anisamide ligand-tethered lipidoid (AA-lipidoid). AA-T3A-C12 mediates great RNA delivery and transfection of activated fibroblasts .
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1 Cited Publications
Cat. No.: HY-148263
Purity: ≥98.0%
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Biotin-PEG2000-Thiol is an active compound. Biotin-PEG2000-Thiol is pegylated by binding to streptavidin or antibiotin with high affinity and specificity. Biotin-PEG2000-Thiol can modify biomolecules, proteins, peptides and other small molecule materials. Biotin-PEG2000-Thiol is widely used in the research of agent release and nano new materials .
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1 Cited Publications
Cat. No.: HY-K0200A
MCE Magnetic Stand Plus features an upgraded design that is compatible with multiple centrifuge tube formats, including 200 μL, 1.5 mL, 2 mL, 5 mL, 10 mL, and 15 mL tubes. It adopts a detachable strong magnetic block design, allowing flexible operation for samples of different volumes and improving both convenience and separation efficiency during experiments.
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1
1 Cited Publications
Cat. No.: HY-W250312
CAS No.: 24980-41-4
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Polycaprolactone is a biodegradable polyester commonly used in various biomedical and industrial applications. It is a white waxy polymer that can be molded into various shapes and forms. Polycaprolactone has various properties suitable for these applications, including low melting point, high flexibility and slow biodegradation rate. It can be used as a raw material for the production of tissue engineering scaffolds, drug delivery systems, and medical implants. In addition, it is used as a binder in the production of adhesives, coatings and paints.
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1 Cited Publications
Cat. No.: HY-48999A
CAS No.: 3033987-42-4
FSK hydrochloride is fluorosulfonyloxybenzoyl-L-lysine, which features a long, flexible aryl fluorosulfate-containing side chain that can reach protein sites inaccessible to covalent conjugation. FSK hydrochloride modifies nanomolecules to target epidermal growth factor receptor (EGFR), resulting in irreversibly bound covalent interactions. Through genetically encoded chemical crosslinking, FSK hydrochloride captures unknown enzyme-substrate interactions in living cells, targets residues other than Cys, and mediates crosslinking at the binding periphery. FSK hydrochloride enables the construction of a bioreactive SuFEx system for generating covalent bonds in various proteins both in vitro and in vivo .
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1 Cited Publications
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DBCO-PEG24-NHS ester is a click chemistry reagent. DBCO-PEG24-NHS ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research use only .
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1 Cited Publications
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DBCO-PEG2-NHS ester is a click chemistry reagent containing an azide group. DBCO-PEG2-NHS ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research use only .
Category:
Infection Antibiotics Microorganism Disease Research Antibacterial Disease Research Fields Other Antibiotics
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Cat. No.: HY-164899
CAS No.: 2765091-45-8
Synonyms: 2-aminopyridine-3-carboxylic acid imidazolide
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2A3 (2-aminopyridine-3-carboxylic acid imidazolide) is a covalent probe reagent for Selective 2'-Hydroxyl Acylation analyzed by Primer Extension (SHAPE) that targets the RNA ribose 2'-OH group. 2A3 efficiently permeates the biological membranes of Gram-negative bacteria, Gram-positive bacteria, and mammalian cells. 2A3 exhibits no base bias and specifically labels conformationally flexible, unpaired regions within RNA.
2A3 forms covalent adducts by acylating the 2'-OH groups of flexible RNA residues. When combined with SHAPE-MaP (mutational profiling) sequencing technology, these modification sites are converted into detectable mutational signals, thereby accurately reflecting local RNA backbone flexibility and base-pairing status. 2A3 is primarily utilized in molecular biology and transcriptomics research, including the resolution of RNA structuromes in living cells, the study of RNA folding regulatory mechanisms, and the investigation of non-coding RNA functions .
Cat. No.: HY-126437E
CAS No.: 25988-63-0
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
