12

12 Publications Verification

Purity: 99.82%

Synonyms: 5-Dodecanoylaminofluorescein di-β-D-Galactopyranoside

C12FDG (5-Dodecanoylaminofluorescein di-β-D-Galactopyranoside) is a lipophilic green fluorescent substrate for β-galactosidase detection. C12-FDG is more sensitive than Fluorescein di(β-D-galactopyranoside) (HY-101895) for beta-galactosidase activity determinations in animal cells (Ex/Em = 488/523 nm) .

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5

Ac-DEVD-AMC

5 Cited Publications

Cat. No.: HY-P1003

CAS No.: 169332-61-0

Target:

Fluorescent Dye

Research Areas:

Others

Ac-DEVD-AMC is a fluorescent substrate of caspase-3/caspase-7. When treating Ac-DEVD-AMC with cell lysate, Ac-DEVD-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection, with an excitation wavelength of 380 nm and an emission wavelength of 460 nm .

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4

Z-Gly-Pro-AMC

4 Cited Publications

Cat. No.: HY-D1670

CAS No.: 68542-93-8

Z-Gly-Pro-AMC is a fluorogenic substrate. Z-Gly-Pro-AMC is hydrolyzed by prolyl endopeptidase to generate highly fluorescent 7-Amino-4-methylcoumarin (HY-D0027). (λ_ex=380 nm, λ_em=465 nm) .

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3

Ac-LEHD-AFC

3 Cited Publications

Cat. No.: HY-P1093

CAS No.: 210345-03-2

Ac-LEHD-AFC is a fluorescent substrate for caspase-9, can be used to assess the activity of caspase .

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3

IDT307

3 Cited Publications

Cat. No.: HY-129096

CAS No.: 1141-41-9

Purity: 99.76%

IDT307, an analog of the organic cation MPP+, is a specific fluorescent substrate for DAT (fluorescent substrate APP+) .

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3

Mca-KPLGL-Dap(Dnp)-AR-NH2

3 Cited Publications

Cat. No.: HY-P4931

CAS No.: 720710-69-0

Target:

MMP

Research Areas:

Cancer

Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 (FS-6) is a fluorescent peptide that is a quenched MMP peptide substrate. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 can be used for real-time quantification of MMP enzymatic activity. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 is an elongated peptide of MMP substrate (FS-1) and is active against collagenases (MMP-1, MMP-8, MMP-13 ) and MT1-MMP with higher specificity constants than FS-1 . (Ex/Em=325 nm/400 nm)

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2

Gly-Pro-AMC hydrobromide

2 Cited Publications

Cat. No.: HY-137834

CAS No.: 115035-46-6

Purity: 98.68%

Gly-Pro-AMC hydrobromide is a fluorescent dye, it can be used as a specific fluorescent substrate for detecting Dipeptidyl peptidase IV (DPP-IV) activity .

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2

Z-Arg-Arg-AMC hydrochloride

2 Cited Publications

Cat. No.: HY-134434

CAS No.: 136132-67-7

Purity: 99.79%

Target:

Cathepsin Fluorescent Dye

Research Areas:

Others

Z-Arg-Arg-AMC hydrochloride is a highly selective fluorescent Cathepsin B substrate. Z-Arg-Arg-AMC hydrochloride can be hydrolyzed by Cathepsin B to produce a fluorescent product for enzyme activity detection .

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2

Z-Gly-Pro-Arg-AMC hydrochloride

2 Cited Publications

Cat. No.: HY-P4217

CAS No.: 201928-42-9

Target:

Biochemical Assay Reagents Cathepsin

Research Areas:

Others

Z-Gly-Pro-Arg-AMC hydrochloride is an AMC-labeled fluorescent peptide substrate used in various in vitro biochemical assays for proteases. Z-Gly-Pro-Arg-AMC hydrochloride releases free AMC upon cleavage of the Arg-AMC peptide bond by proteases, generating a fluorescent signal. Z-Gly-Pro-Arg-AMC hydrochloride is efficiently hydrolyzed by CatCΔEx and recombinant proMlCtL, and can also serve as a detection substrate for KLK family proteases .

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2

Suc-Gly-Pro-AMC

2 Cited Publications

Cat. No.: HY-145983

CAS No.: 80049-85-0

Purity: 99.16%

Target:

FAP Prolyl Endopeptidase (PREP)

Research Areas:

Cancer

Suc-Gly-Pro-AMC is a fluorescent substrate. Suc-Gly-Pro-AMC is a fibroblast activation protein (FAP) specific substrate. Suc-Gly-Pro-AMC reacts with recombinant porcine prolyl oligopeptidase. Suc-Gly-Pro-AMC can be used to study the activity of FAP, prolyl endopeptidase (PREP). Suc-Gly-Pro-AMC is used in glioma research .

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2

Ac-VDVAD-AFC TFA

2 Cited Publications

Cat. No.: HY-P2615A

Target:

Fluorescent Dye

Research Areas:

Cancer

Ac-VDVAD-AFC TFA is a caspase-specific fluorescent substrate. Ac-VDVAD-AFC TFA can measure caspase-3-like activity and caspase-2 activity and can be used for the research of tumor and cancer .

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2

Coumberone

2 Cited Publications

Cat. No.: HY-D1341

CAS No.: 878019-47-7

Research Areas:

Cancer

Coumberone is a metabolic fluorogenic probe, and isoform-selective substrate for all AKR1C isoforms. Coumberone can be reduced by all four members of the AKR1C family to its fluorescent alcohol coumberol. Coumberone can be used for the research of AKR1C .

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2

7-Azido-4-methylcoumarin

2 Cited Publications

Cat. No.: HY-119323

CAS No.: 95633-27-5

Purity: 99.11%

Target:

Fluorescent Dye

Research Areas:

Others

7-Azido-4-methylcoumarin is a selective coumarin-based fluorescent probe for hydrogen sulfide (H₂S). In the presence of H₂S, the aromatic azido group of 7-Azido-4-methylcoumarin is selectively reduced to produce the fluorescently active 7-amino-4-methylcoumarin (AMC). 7-Azido-4-methylcoumarin binds to the coumarin/phenol-binding site of BSA, the aglycone-binding site of UGT1A6, and the substrate-binding site of SULT1A1, respectively. 7-Azido-4-methylcoumarin retains its fluorescent properties after covalent binding, acts as a fluorescent H₂S probe, and does not react with cysteine, homocysteine or glutathione (Ex/Em = 340/445 nm) .

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2

4-MUNANA

2 Cited Publications

Cat. No.: HY-W019823

CAS No.: 76204-02-9

4-MUNANA is a substrate of influenza virus neuraminidase (NA) with high selectivity and irreversible reaction. In the enzymatic reaction, 4-MUNANA is hydrolyzed by NA to generate fluorescent 4-methylumbelliferone (4-MU). By detecting the fluorescence intensity of 4-MU, quantitative analysis of NA activity can be achieved. 4-MUNANA can be used in influenza-related research, such as screening NA inhibitors, developing new anti-influenza drugs, and studying the infection mechanism of influenza viruses .

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2

Tamarixetin

2 Cited Publications

Cat. No.: HY-N1181

CAS No.: 603-61-2

Synonyms: 4'-O-Methyl Quercetin

Category:

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Fluorescent substrate

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