110 Results for "

Fmoc protecting groups

" in MedChemExpress (MCE) Product Catalog:
Products (110)

110 Results for "Fmoc protecting groups" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-W010712
CAS No.: 109425-51-6
Research Areas:  

Others

Fmoc-His(Trt)-OH is a histidine derivative with a trityl (Trt) group protecting the His side chain. Fmoc-His(Trt)-OH also has an Fmoc group protecting the α-NH2 group. Fmoc-His(Trt)-OH can be used in solid-phase peptide synthesis to prevent racemization and byproduct formation. Fmoc-His(Trt)-OH acts as a protected histidine precursor in solid-phase peptide synthesis (SPPS), participating in peptide chain construction through amide bond formation. Fmoc-His(Trt)-OH can be precisely incorporated into the target peptide sequence, ensuring correct peptide chain synthesis and reducing impurity formation. Fmoc-His(Trt)-OH is mainly used in the solid-phase synthesis research of pharmaceutical peptides and bioactive peptides, and is particularly suitable for the preparation of peptide drugs requiring precise control of histidine configuration .
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1
1 Cited Publications
Cat. No.: HY-W013081
CAS No.: 132327-80-1
Fmoc-Gln(Trt)-OH is a glutamine derivative containing amine protecting group Fmoc. Fmoc-Gln(Trt)-OH can be used in solid-phase peptide synthesis .
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Cat. No.: HY-Y1636
CAS No.: 154445-77-9
Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis) .
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Cat. No.: HY-Y1169
CAS No.: 71989-14-5
Synonyms: 4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate; Fmoc-L-Asp(OtBu)-OH
Research Areas:  

Others

Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is an aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis .
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Cat. No.: HY-79647
CAS No.: 82911-69-1
Synonyms: N-(Fmoc-oxy)succinimide
Fmoc-OSu (N-(Fmoc-oxy)succinimide) is an acylating agent that targets amino groups (-NH2). It can selectively protect the amino groups of amino acids by covalently binding with primary or secondary amines through nucleophilic substitution reactions. Fmoc-OSu forms a stable amide bond with the amino group to avoid side reactions of the amino group in peptide synthesis. It can also be used as a fluorescent labeling reagent to react with glycosylamines for efficient labeling of N-sugar chains. Fmoc-OSu can be used as an Fmoc protection strategy in peptide synthesis, and as a fluorescent labeling and analysis method for N-sugar chains .
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Cat. No.: HY-W048739
CAS No.: 312624-65-0
Research Areas:  

Others

Fmoc-α-Me-Leu-OH is a leucine derivative with an Fmoc protecting group, which can be used to synthesize peptides with oxytocin receptor agonist activity .
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Cat. No.: HY-W048688
CAS No.: 1334509-86-2
Research Areas:  

Others

Fmoc-Trp(Me)-OH is an amino acid derivative. Fmoc-Trp(Me)-OH is formed by introducing a methyl group onto the nitrogen atom (N-1 position) of the indole ring of tryptophan (Trp) and protecting the amino group with Fmoc (9-fluorenylmethyloxycarbonyl). Fmoc-Trp(Me)-OH can be used in the synthesis of proteins or peptides .
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Cat. No.: HY-W008876
CAS No.: 201531-88-6
Research Areas:  

Others

Fmoc-Pen(Trt)-OH is an amino acid derivative with an Fmoc protecting group that can be used to synthesize the inhibitory cystine knot (ICK) peptide ProTx-II .
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Cat. No.: HY-137002
CAS No.: 913733-27-4
Research Areas:  

Others

Fmoc-N-Me-Arg(Pbf)-OH is an amino acid derivative containing a guanidinium protecting group on the arginine side chain. Fmoc-N-Me-Arg(Pbf)-OH is used in the synthesis of neurotensin-derived NTS1 ligands for PET imaging .
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Cat. No.: HY-W010922
CAS No.: 162558-25-0
Research Areas:  

Others

Fmoc-Dap (Boc)-OH is an amino acid derivative bearing the Fmoc protecting group. Fmoc-Dap (Boc)-OH supports Fmoc-based solid-phase peptide synthesis for the preparation of bicyclic tachykinin NK2 receptor antagonists .
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Cat. No.: HY-W007056
CAS No.: 197632-75-0
Research Areas:  

Infection

Fmoc-N-me-Trp(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize peptide antibiotics with antibacterial activity against Pseudomonas aeruginosa .
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Cat. No.: HY-W008064
CAS No.: 133174-15-9
Synonyms: Fmoc-L-Citrulline
Research Areas:  

Cancer

Fmoc-Cit-OH (Fmoc-L-Citrulline) is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize a degradable ADC linker composed of a valine-citrulline (Val-Cit) motif .
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Cat. No.: HY-W425682
CAS No.: 1403693-21-9
Target:  

Drug Intermediate

Research Areas:  

Others

Fmoc-L-Penicillamine is formed by the connection of the Fmoc protecting group and L-Penicillamine through a specific chemical bond. Fmoc-L-Penicillamine plays an important role in organic synthesis, especially in the field of peptide synthesis .
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Cat. No.: HY-W009118
CAS No.: 123622-48-0
Research Areas:  

Others

Fmoc-5-Ava-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize fatty acid-based dimeric peptides with PSD-95 inhibitory activity .
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Cat. No.: HY-W013154
CAS No.: 136030-33-6
Research Areas:  

Others

Fmoc-Tic-OH, an Fmoc-protected derivative of Tic, is a solid-phase peptide synthesis monomer. Fmoc-Tic-OH protects the amino group of Tic via a base-labile Fmoc group, allowing conformationally constrained Tic residues to be stepwise coupled to peptide chains, and the Fmoc protecting group can be removed under piperidine conditions. Fmoc-Tic-OH can be used for peptide synthesis and opioid receptor ligand research .
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Cat. No.: HY-79255
CAS No.: 863971-38-4
Research Areas:  

Cancer

Fmoc-MMAF-OMe is an anticancer agent and tubulin polymerization inhibitor with an Fmoc protecting group. The active ingredient of Fmoc-MMAF-OMe, MMAF (HY-15579), is the cytotoxic (ADC Cytotoxin) component of classic antibody drug conjugates (ADCs) .
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Cat. No.: HY-W015987
CAS No.: 84418-43-9
Synonyms: Fmoc-NH2
Research Areas:  

Others

9-Fluorenylmethyl carbamate (Fmoc-NH2) is an amide compound with an Fmoc protecting group, which can be used as a photobase initiator to prepare organosilane-based proton exchange membranes .
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Cat. No.: HY-W048697
CAS No.: 201532-01-6
Research Areas:  

Others

Fmoc-D-Pen(Trt)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize analogs of cyclic lanthionine enkephalin, a δ-opioid receptor selective ligand .
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Cat. No.: HY-W097128
CAS No.: 128917-74-8
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Fmoc-12-aminododecanoic acid is an alkane chain with terminal Fmoc-protected amine and carboxylic acid groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
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Cat. No.: HY-W008024
CAS No.: 125238-99-5
Research Areas:  

Others

Fmoc-Dab(Boc)-OH (Compound 5) is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize agents that inhibit neointimal formation induced by rat balloon injury. Fmoc-Dab(Boc)-OH serves as an intermediate for the synthesis of bioactive peptides or their analogs .
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