Synonyms: 6-Desoxygalactose; L-(-)-Fucose; L-Galactomethylose

Category:

Human Gut Microbiota Metabolites Metabolic Disease Endogenous metabolite Disease Research Fields Saccharides Monosaccharides

Target:

Endogenous Metabolite Parasite

(-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interactions. (-)-Fucose is orally active, inhibits CL11-induced inflammatory response in kidney and tumor growth .

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5

2F-Peracetyl-Fucose

5 Cited Publications

Cat. No.: HY-W096600

CAS No.: 188783-78-0

Synonyms: 1,3,4-Tri-O-acetyl-2-deoxy-2-fluoro-L-fucopyranos

Target:

Glycosyltransferase

Research Areas:

Cancer

2F-Peracetyl-Fucose (1,3,4-Tri-O-acetyl-2-deoxy-2-fluoro-L-fucopyranos) acts as a potent fucosyltransferase (FUT) inhibitor .

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3

2-Deoxy-2-fluoro-L-fucose

3 Cited Publications

Cat. No.: HY-116705

CAS No.: 70763-62-1

Purity: 99.99%

Target:

Glycosyltransferase

Research Areas:

Cancer

2-Deoxy-2-fluoro-L-fucose, an L-fucose analog, is a fucosylation inhibitor. 2-Deoxy-2-fluoro-L-fucose inhibits de novo synthesis of GDP-fucose in mammalian cells. Fucosylation is a relatively well-defined biomarker for progression in many human cancers; for example, pancreatic and hepatocellular carcinoma .

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1

GDP-L-fucose

1 Cited Publications

Cat. No.: HY-134433

CAS No.: 15839-70-0

Purity: 99.82%

Category:

Human Gut Microbiota Metabolites Natural Products Metabolic Disease Endogenous metabolite Disease Research Fields

Target:

Endogenous Metabolite

GDP-L-fucose is a nucleotide sugar that is a key substrate for the biosynthesis of fucose oligosaccharides, providing the fucose moiety for the oligosaccharides.The formation of GDP-L-fucose occurs through two pathways, the major ab initio metabolic pathway and the minor remedial metabolic pathway. GDP-L-fucose is associated with diabetes in rats .

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1

GDP-L-fucose disodium

1 Cited Publications

Cat. No.: HY-134433A

CAS No.: 148296-47-3

Purity: 99.78%

Category:

Natural Products Metabolic Disease Endogenous metabolite Disease Research Fields

Target:

Endogenous Metabolite

GDP-L-fucose disodium is a nucleotide sugar that is a key substrate for the biosynthesis of fucose oligosaccharides. GDP-L-fucose disodium provides the fucose moiety for the oligosaccharides. The formation of GDP-L-fucose disodium occurs through two pathways, the major de novo metabolic pathway and the minor remedial metabolic pathway .

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1

Fucosyltransferase 8

1 Cited Publications

Cat. No.: HY-E70157

Synonyms: EC:2.4.1.68; FUT8; α1-6FucT

Fucosyltransferase 8 (EC:2.4.1.68; FUT8; α1-6FucT) is a glycosyl transferase and catalyzes the transfer of a fucose residue from GDP-fucose to the innermost N-acetylglucosamine residue of N-glycans .

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1

(-)-Fucose (Standard)

1 Cited Publications

Cat. No.: HY-N1480R

CAS No.: 2438-80-4

Synonyms: 6-Desoxygalactose (Standard); L-(-)-Fucose (Standard); L-Galactomethylose (Standard)

Category:

Human Gut Microbiota Metabolites Natural Products Microorganisms Endogenous metabolite

Target:

Reference Standards Endogenous Metabolite Parasite

(-)-Fucose (Standard) is the analytical standard of (-)-Fucose. This product is intended for research and analytical applications. (-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interactions. (-)-Fucose is orally active, inhibits CL11-induced inflammatory response in kidney and tumor growth .

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1

alpha-1,3-Fucosyltransferase (α1,3FucT)

1 Cited Publications

Cat. No.: HY-E70064

CAS No.: 37277-69-3

Target:

Endogenous Metabolite

Research Areas:

Others

alpha-1,3-Fucosyltransferase (α1,3FucT) catalyzes the transfer of L-fucose moiety from guanosine diphosphate-beta-L-fucose (GDP-Fuc) to acceptor sugars. alpha-1,3-Fucosyltransferase (α1,3FucT) is often used in biochemical studies, and it can be used to form fucoglycoconjugates .

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Inebilizumab (FUT8-KO)

Cat. No.: HY-P99113A

Inebilizumab (FUT8-KO) is an anti-CD19 monoclonal antibody expressed by CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out. Fucose deficiency enhances the antibody-dependent cellular cytotoxicity (ADCC) effect of the antibody.Inebilizumab (FUT8-KO) exhibits enhanced ADCC against B cells and can be used for research on multiple sclerosis and neuromyelitis optica .

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