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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
GABA-AT
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "GABA-AT" in MCE Product Catalog:
Target:
Research Areas:
3-Aminobenzoic acid (3-ABA) is an orally active anti-inflammatory agent targeting the tight junction (TJ) regulatory pathways in intestinal epithelial cells. 3-Aminobenzoic acid improves intestinal inflammation by enhancing intestinal barrier integrity and reducing epithelial permeability. It can be used in studies related to improving gut health. Additionally, 3-Aminobenzoic acid analogs can act as γ-aminobutyric acid transaminase (GABA-AT) inhibitors, exhibiting anticonvulsant effects .
Cat. No.: HY-147982
CAS No.: 242148-96-5
Target:
Research Areas:
GABA-AT-IN-1 (Compound 6) is a γ-aminobutyric acid aminotransferase (GABA-AT) inhibitor and significantly elevates the mouse brain GABA level. GABA-AT-IN-1 has the ability to cross the BBB and can be used as an anticonvulsant .
Cat. No.: HY-P72068
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ABAT; GABA-T; 4-AminobutyrATe Aminotransferase; Gamma-AminobutyrATe Aminotransferase; GABAT; 4-AminobutyrATe Transaminase; 4-AminobutyrATe Aminotransferase, Mitochondrial; GABA-AT; (S)-3-Amino-2-MethylpropionATe Transaminase; L-AIBAT; Gamma-Amino-N-Butyra
Species:
Human
Source:
E. coli
Cat. No.: HY-RS00036
Target:
Research Areas:
ABAT Human Pre-designed siRNA Set A contains three designed siRNAs for ABAT gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-180087
CAS No.: 898468-56-9
Target:
Research Areas:
GABA-AT-IN-2 (compound 11g) is a GABA aminotransferase (GABA-AT) inhibitor with an IC50 of 19.8 μM. GABA-AT-IN-2 demonstrates notable antianxiety effects in mice. GABA-AT-IN-2 can be used for anxiety-related neurotic disorders research .
Research Areas:
3-Aminobenzoic acid (Standard) is the analytical standard of 3-Aminobenzoic acid. This product is intended for research and analytical applications. 3-Aminobenzoic acid (3-ABA) is an orally active anti-inflammatory agent targeting the tight junction (TJ) regulatory pathways in intestinal epithelial cells. 3-Aminobenzoic acid improves intestinal inflammation by enhancing intestinal barrier integrity and reducing epithelial permeability. It can be used in studies related to improving gut health. Additionally, 3-Aminobenzoic acid analogs can act as γ-aminobutyric acid transaminase (GABA-AT) inhibitors, exhibiting anticonvulsant effects .
Cat. No.: HY-RS18027
Target:
Research Areas:
Abat Mouse Pre-designed siRNA Set A contains three designed siRNAs for Abat gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-W1025152
CAS No.: 760947-97-5
Research Areas:
CPP-115 hydrochloride is an orally active, selective GABA-AT inhibitor with a Ki value of 9.7 μM. CPP-115 hydrochloride blocks GABA degradation and increases GABA levels in the brain. CPP-115 hydrochloride does not bind to GABA transporters, does not displace GABA from GABAA/GABAB receptors, and does not act as an agonist/antagonist of GABAC receptors. CPP-115 hydrochloride reduces cocaine-induced dopamine release, blocks cocaine-induced conditioned place preference, and suppresses seizure activity in a rat model of infantile spasms. CPP-115 hydrochloride can be used in research related to infantile spasms and epilepsy .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
