Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
GC base pair
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "GC base pair" in MCE Product Catalog:
6
6 Cited Publications
Cat. No.: HY-D1191
CAS No.: 2225748-05-8
2
2 Cited Publications
Cat. No.: HY-114577
CAS No.: 1070409-31-2
Synonyms: Isophosphoramide mustard tromethamine; IPM tromethamine; ZIO-201 tromethamine
Target:
Research Areas:
Palifosfamide (tromethamine) is a synthetic alkylating agent with potential antineoplastic activity. As the stabilized active metabolite of ifosfamide, palifosfamide (tromethamine) irreversibly alkylates and crosslinks DNA through GC base pairs. This leads to an inhibition of DNA replication and ultimately cell death. Compared to ifosfamide, palifosfamide (tromethamine) is less toxic.
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
