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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
GK444
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "GK444" in MCE Product Catalog:
Cat. No.: HY-155328
CAS No.: 3032392-39-2
Target:
Research Areas:
GK444 is a selective HDAC1, HDAC2 and HDAC3 inhibitor with IC50 values of 100 nM, 116 nM and 361 nM, respectively. GK444 reduces TGF-β1-induced COL1A1 mRNA levels. GK444 exhibits anticancer activity against lung cancer, astrocytoma and colorectal cancer. GK444 exerts antifibrotic effects in Bleomycin (HY-108345)-induced pulmonary fibrosis mouse models .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
